Design,Synthesis& Pharmacological Screening of Some Novel Heterocycles

Design,Synthesis& Pharmacological Screening of Some Novel Heterocycles

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Synthesis of nitrogen and sulphur heterocycles is of current interest because of their broad spectrum biological activities.The heterocycles such as 1,5-benzothiazepine, indole, azetidinone have gained attention of medicinal chemists due to their use as drugs and medicaments in a large number of diseases. The thesis work reports design and synthesis of these mentioned pharmacologically active heterocycles and coupled heterocycles bearing appropriate pharmacophores needed for anti convulsant, CNS depressant and antifungal actvities. The aromatic rings , heterocyclic substituents and one / two h...