During the last few decades there has been an increasing interest in the study of medicinal plants and their traditional use in different parts of India by either tribal people or indigenous communities. The present study deals with the enumeration of medicinally important indigenous plants belonging to various families frequently used by local communities of Meja tehsil of Allahabad district, Uttar Pradesh for the treatment of various diseases like skin diseases, diabetes, weakness, cold and cough, poison bites, diarrhea, asthma, fever, rheumatic pain, oral diseases, fracture, jaundice and tuberculosis etc. During the study, 98 persons (55 male and 43 females) were contacted to know about the indigenous plants used for medicinal purposes. This information need to be tested and validated for further bioprospecting and commercial activities.