Synthesis and biological activity of schiff-base bearing moieties. - Panchal, Vikram;Variya, Hiren;Vora, Manoj
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The newly synthesized two series namely: (E)-2-benzylidene-N-(2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)acetyl) hydrazinecarboxamide /(E)-2-benzylidene-N-(2-((5-phenyl-1,3,4-oxadiazol-2-yl) thio) ethanethioyl) hydrazine carboxamide (OS1 to OS18) were prepared. These compounds synthesized from 5-phenyl-1,3,4-oxadiazole-2-thiol, Thiosemicarbazide (TSC) and Semicarbazide (SC) were vital functionalities containing the wide range of Pharmacological activities and have a wide range of therapeutic properties. The structure of the synthesized compounds was confirmed by spectral data and evaluated for…mehr

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Produktbeschreibung
The newly synthesized two series namely: (E)-2-benzylidene-N-(2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)acetyl) hydrazinecarboxamide /(E)-2-benzylidene-N-(2-((5-phenyl-1,3,4-oxadiazol-2-yl) thio) ethanethioyl) hydrazine carboxamide (OS1 to OS18) were prepared. These compounds synthesized from 5-phenyl-1,3,4-oxadiazole-2-thiol, Thiosemicarbazide (TSC) and Semicarbazide (SC) were vital functionalities containing the wide range of Pharmacological activities and have a wide range of therapeutic properties. The structure of the synthesized compounds was confirmed by spectral data and evaluated for their in vitro antibacterial and antifungal activities against fungi, Gram-positive and Gram-negative bacteria.
Autorenporträt
Dr. Vikram Panchal secured a master degree in Inorganic Chemistry. His doctoral research is in Organic chemistry. He has worked as an assistant professor in Sal Eductional campus.