There are various developed instruments to assess impact of asthma among asthmatic children but few of these instruments were developed in paired versions of child and caregiver. Children Health Survey for Asthma is one of the instruments that have paired versions, parent version (CHSA) (item, n = 48) and child version (CHSA-C) (item, n = 25). The aims of the present study were to establish the validity and reliability of the Malaysian versions of M-CHSA and M-CHSA-C, to assess the effect of asthma on Malaysian asthmatic children and their parents, to present the difference of child's and parent's report about the effect of asthma on their lives, and to investigate the differences, effects and relationships of socio-demographic and medical data with the health outcomes from asthmatic children and their parents.