Aloe Vera is a medicinal plant used since ancient times and cultivated in many warm regions of the world. A large amount of active ingredients and therapeutic properties are known in Aloe Vera. Aloe has been variously used for civilian and traditional medical purposes worldwide for thousands of years, and today it remains in use as a self-medication in western and under-developed countries. As such, Aloe's possession of various functions has been clinically proven. It is truly one of the very few plants that are used in such a profusion of applications. Medical plants are the best source for getting treatment from various diseases. Using of natural substances with therapeutic properties has been used since ancient times. More than 500 species of Aloe Vera are known. This plant is native to tropical areas, including the north of Africa, Europe and the southern part of the Mediterranean region. Aloe Vera grows widely in the south of Iran and is cultured for the pharmaceutical uses.Aloe Vera is a plant with structural and physiological adaptations that allow it to survive in arid or semiarid regions with erratic rainfall. Aloe is a medicinal plant cultivated for various applications.