Dipankar Chattopadhyay, Jonathan Tersur Orasugh, Md Adhikari MBBS, Suprakas Sinha Ray

Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery (eBook, ePUB)

• Format: ePub

Produktbeschreibung

This book covers fundamental aspects in the preparation of polymeric in-situ, stimuli-responsive hydrogels; the properties, characterization, chemistry, and fabrication of these hydrogels is detailed, helping the reader to select the most appropriate material and design for the desired application. The book goes on to review applications in ophthalmic drug delivery, covering in vitro and in vivo models, animal models, preclinical testing, patents and more. Stimuli-responsive Hydrogels for Ophthalmic Drug Delivery is a must-have reference for researchers and academics in the fields of materials science, biomaterials, pharmacology and polymer science, with an interest in clinical aspects of hydrogel design and application.

• Provides step-by-step coverage for engineering in-situ and stimuli-responsive hydrogels, from design, characterization, and toxicity considerations to fabrication, process optimization, and drug release kinetics
• Utilizes an interdisciplinary approach, bringing together authors from pharmacology, polymer science, and medical backgrounds
• Details the advantages and challenges of using stimuli-responsive hydrogels for ophthalmic drug delivery, with a focus on clinical translation

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 500
• Erscheinungstermin: 8. Mai 2024
• Englisch
• ISBN-13: 9780323993593
• Artikelnr.: 70622162

Autorenporträt

Prof. Dipankar Chattopadhyay is an eminent professor currently working in the Department of Polymer Science & Technology, University of Calcutta, India since 2006 and also a former HOD. Earlier, he worked as a lecturer at the Vidhyasagar University and Shahid Bhagat Singh College, Punjab, India. He obtained his B.Tech in Plastics & Rubber Technology from University of Calcutta, India and M.Tech in Polymer Science and Engineering, IIT, New Delhi with Ph.D. (Polymer Science) from the IACS, India. He is an experienced research professional with expertise in polymers nanocomposites, biomaterials, and nanomaterials. He has ~22 years of research experience with completed 10 research project and collaborative projects with industries. He is an active reviewer for various Journals and supervised >20 scholars and five post-doctorate students. He has 127 publications and has 3 patents. He is an Executive Member in the Society for Polymer Science, India; MRSI, Calcutta Chapter and many more.

Inhaltsangabe

Part I: Properties and Preparation 1. Introduction to polymeric in-situ
forming hydrogels 2. Biopolymers for in-situ forming hydrogels: synthesis,
characterization, and toxicity 3. Chemistry and applications of biopolymer
stimuli-responsive in-situ gels 4. Design, engineering, and fabrication of
biopolymer in-situ forming hydrogels 5. Process optimization for design and
fabrication of biopolymer stimuli-responsive hydrogels 6. Properties of
biopolymeric in-situ hydrogels 7. Swelling and drug release kinetics of
biopolymer in-situ forming hydrogels 8. Structural and load-bearing
characteristics of biopolymer in-situ forming hydrogels 9.
Functionalization of in-situ forming biopolymer hydrogels Part II:
Applications in Ophthalmic Drug Delivery 10. Eye anatomy, physiology, and
ocular barriers 11. In vitro and in vivo models in ophthalmic drug delivery
12. Formulation and ocular drug delivery routes 13. Clinical indications of
stimuli-responsive hydrogels in ophthalmic drug delivery 14. Natural and
synthetic materials for stimuli-responsive hydrogels in ophthalmic drug
delivery 15. Characteristics and kinetics of in-situ forming hydrogels in
ophthalmic drug delivery 16. Cell-laden stimuli-responsive hydrogels in
ophthalmic drug delivery 17. Animal models and preclinical tests for
evaluation of stimuli-responsive hydrogels in ophthalmic drug delivery 18.
Biopolymer-based in-situ forming hydrogels: from laboratory to practical
application 19. Commercially available stimuli-responsive hydrogels for
ophthalmic drug delivery 20. Advantages and challenges of biopolymer
in-situ hydrogels for ophthalmic drug delivery 21. Patents for biopolymer
in-situ hydrogels for ophthalmic drug delivery