Nanotechnology and Brain Cancer Treatment - Minoo, Shima;Rezaei, Fatemeh;Mostafavi, Mehrnaz
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Brain cancer has a poor prognosis and limited treatment options, with traditional methods facing challenges like poor drug penetration across the BBB, non-specific distribution, and harsh side effects. However, recent advances in nanotechnology provide new hope for addressing these issues and improving patient outcomes. Nanocarriers, including polymeric nanoparticles, solid lipid nanoparticles, dendrimers, micelles, and liposomes, show promising results. Advantages include EPR, extended circulation, controlled release, and increased cellular uptake. Active targeting enables precise…mehr

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Produktbeschreibung
Brain cancer has a poor prognosis and limited treatment options, with traditional methods facing challenges like poor drug penetration across the BBB, non-specific distribution, and harsh side effects. However, recent advances in nanotechnology provide new hope for addressing these issues and improving patient outcomes. Nanocarriers, including polymeric nanoparticles, solid lipid nanoparticles, dendrimers, micelles, and liposomes, show promising results. Advantages include EPR, extended circulation, controlled release, and increased cellular uptake. Active targeting enables precise localization of therapeutics at tumor sites, enhancing effectiveness and minimizing off-target impacts. Multifunctional nanosystems also allow simultaneous diagnostics and therapeutics (theranostics). While there are still barriers like BBB penetration, scalability, and regulation, ongoing research continues to reveal innovative solutions, bringing fresh hope to those afflicted with this deadly disease.
Autorenporträt
Dr. Shima Minoo has received her Doctor of Dentistry (D.D.S.) degree from Isfahan Azad University of Iran. She has published some papers in well-known journals. Her interests are biomaterial, biology, dental material, tissue regeneration, neuroscience and nanotechnology in dentistry.