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This book presents a simplified resume of the structure of nail apparatus.It also discuss the clinical types of onychomycosis and different causative organismsIt reports the conventional and updated antifungal therapiesThis book presents the latest updates in laser treatment of onychomycosisLaser treatment of onychomycosis is an excellent alternative to treat onychomycosis in those refusing, un-responding or contraindicated to receive systemic antifungal therapyWe present our work on laser treatment of onychomycosis that have been published in Lasers in Surgery and Medicine Journal "Long pulsed Nd:YAG (1064 nm ) laser versus Q-switched Nd:YAG (1064nm) for treatment of onychomycosis."