Brian A. Baldo, Nghia H. Pham

Drug Allergy (eBook, PDF)

Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships

• Format: PDF

Produktbeschreibung

The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms.

This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies.

The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.

Produktdetails

• Verlag: Springer International Publishing
• Erscheinungstermin: 8. Dezember 2020
• Englisch
• ISBN-13: 9783030517403
• Artikelnr.: 61344391

Autorenporträt

Brian A. Baldo (Retired)
AUA (Pharmacy); BSc(Hons); PhD Formerly: Head, Molecular Immunology Unit Kolling Institute of Medical Research Royal North Shore Hospital of Sydney and University of Sydney Sydney, NSW, Australia Nghia H. Pham (Retired) MSc; PhD Formerly: Molecular Immunology Unit Kolling Institute of Medical Research Royal North Shore Hospital of Sydney and University of Sydney Sydney, NSW, Australia

Inhaltsangabe

Ch. 1. Adverse reactions to drugs and drug allergy.- Ch. 2. Classification and descriptions of allergic reactions to drugs.- Ch. 3. Mechanisms of hypersensitivity.- Ch. 4. Diagnosis of allergic reactions to drugs.- Ch. 5. Beta-Lactam antibiotics.- Ch. 6. Other antimicrobial drugs.- Ch. 7. Drugs and other agents used in anesthesia and surgery.- Ch. 8. Opioid analgesic drugs.- Ch. 9. Nonsteroidal anti-inflammatory drugs.- Ch. 10. Contrast media.- Ch. 11. Corticosteroids.- Ch. 12. Proton pump inhibitors.- Ch. 13. Targeted drugs for cancer therapy. Approved monoclonal antibodies.- Ch. 14. Non-targeted drugs for cancer therapy.- Ch. 15. Other approved therapeutic monoclonal antibodies.- Ch. 16. Other biologics.- Ch. 17. Vaccines.

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Ch. 1. Adverse reactions to drugs and drug allergy.- Ch. 2. Classification and descriptions of allergic reactions to drugs.- Ch. 3. Mechanisms of hypersensitivity.- Ch. 4. Diagnosis of allergic reactions to drugs.- Ch. 5. Beta-Lactam antibiotics.- Ch. 6. Other antimicrobial drugs.- Ch. 7. Drugs and other agents used in anesthesia and surgery.- Ch. 8. Opioid analgesic drugs.- Ch. 9. Nonsteroidal anti-inflammatory drugs.- Ch. 10. Contrast media.- Ch. 11. Corticosteroids.- Ch. 12. Proton pump inhibitors.- Ch. 13. Targeted drugs for cancer therapy. Approved monoclonal antibodies.- Ch. 14. Non-targeted drugs for cancer therapy.- Ch. 15. Other approved therapeutic monoclonal antibodies.- Ch. 16. Other biologics.- Ch. 17. Vaccines.

Rezensionen

"The second edition of the book Drug Allergy is a comprehensive textbook that encompasses the most current knowledge on drug allergy and hypersensitivity. ... The book is a reference for clinicians, surgeons, pharmacists, nurses, and medical students, and provides the research background to guide the next generation of studies to fill the unmet needs in drug allergy and advance the field." (Mariana Castells, Annals of Allergy, Asthma & Immunology, Vol. 128 (5), May, 2022)

From the reviews:

"The current book offers valuable knowledge regarding mechanisms, clinical aspects, diagnostic methods, and therapeutic approach in drug allergy, which will aid the caring physician to successfully diagnose and manage affected individuals. ... The summary points at the end of each chapter represent an outstanding feature of this book. As a comprehensive overview of the mechanisms, clinical manifestations and diagnostic methods in drug allergy will provide valuable and practical information for every physician interested in this disease." (Juan Carlos Aldave, World Allergy Organization, worldallergy.org, February, 2014)

"Book presents the science behind what truly is an allergic reaction to guide evidence-based decisions on drug therapy. It addresses the clinical aspects of allergy in addition to the mechanism of disease, the molecular chemistry behind allergy, and other key features. ... Although this can be a valuable reference for anyone in healthcare, the primary audience is composed of physicians, pharmacists, and nurses, as well as students ... . a great reference for those who wish more information or are preparing lectures on this topic." (Patrick J. McDonnell, Doody's Book Reviews, October, 2013)