Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative…mehr
Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts. With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer.
Dr. Ankit Jain is currently working as a Postdoctoral Research Associate at Texas A&M University School of Pharmacy, Texas. He completed his B. Pharm. (2006-09), M. Pharm. (Pharmaceutics, 2009-11), and Ph.D. (2012-17). Dr. Jain has been exploring different vesicular carriers viz. liposomes, niosomes, and micelles for the last eleven years. He has earmarked an appreciation for his outstanding performance in academics. He has been conferred with the "MP Young Scientist Award- 2017?. He has published 60 International publications in journals of high repute (Citations = 2500+, h-index = 21, and I10-index = 55) along with 25 book chapters in International Books. He is a reviewer and editorial board member of different renowned journals of international publishers An overarching goal of his current research is the development of nano-engineered drug delivery systems for various diseases with a prime focus on cancer
Inhaltsangabe
1. Anomalous tumour microenvironment: exploitable features for drug delivery 2. Vesicular carriers for stimuli-responsive drug delivery to tumours: design considerations 3. Role of dePEGylation in vesicular carriers mediated stimuli-responsive drug delivery to tumours 4. pH-responsive vesicular carriers as promising tools for tumour targeting 5. Enzyme-responsive vesicular carriers as an emerging approach for tumour targeting 6. Redox-responsive vesicular carriers for potential tumour-targeting applications 7. Hypoxia-responsive vesicular carriers for enhanced tumour targeting 8. Magnetically responsive and thermo-responsive vesicular carriers for improved drug delivery to tumours 9. Ultrasound-responsive vesicular carriers for tumour targeting 10. Light-triggered vesicular carriers for tumour targeting 11. Electro- and Mechano-responsive vesicular carriers targeting tumours 12. Emerging applications of stimuli-responsive novel vesicular carriers: Exosomes, supramolecular vesicles, and catanionic vesicles 13. Vesicular carriers with multipronged features for diagnostics and theranostics 14. Nanotoxicity and challenges in stimuli-responsive vesicular carriers targeting tumour 15. Patents, clinical trials, and regulatory concerns with stimuli-responsive vesicular carriers.
1. Anomalous tumour microenvironment: exploitable features for drug delivery 2. Vesicular carriers for stimuli-responsive drug delivery to tumours: design considerations 3. Role of dePEGylation in vesicular carriers mediated stimuli-responsive drug delivery to tumours 4. pH-responsive vesicular carriers as promising tools for tumour targeting 5. Enzyme-responsive vesicular carriers as an emerging approach for tumour targeting 6. Redox-responsive vesicular carriers for potential tumour-targeting applications 7. Hypoxia-responsive vesicular carriers for enhanced tumour targeting 8. Magnetically responsive and thermo-responsive vesicular carriers for improved drug delivery to tumours 9. Ultrasound-responsive vesicular carriers for tumour targeting 10. Light-triggered vesicular carriers for tumour targeting 11. Electro- and Mechano-responsive vesicular carriers targeting tumours 12. Emerging applications of stimuli-responsive novel vesicular carriers: Exosomes, supramolecular vesicles, and catanionic vesicles 13. Vesicular carriers with multipronged features for diagnostics and theranostics 14. Nanotoxicity and challenges in stimuli-responsive vesicular carriers targeting tumour 15. Patents, clinical trials, and regulatory concerns with stimuli-responsive vesicular carriers.
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