Sahar Khalil, Gehad Hammouda, Somaya Hosny

Replicative Cessation & DNA Damage in Human Fibroblast under Stress

A study to investigate the replicative cessation, morphology and DNA damage in human fibroblasts under stress conditions

• Broschiertes Buch

Produktbeschreibung

Aging can be viewed partly as a degenerative process dictated by free radical reactions. Human diploid fibroblasts (HDFs) lose the capacity to proliferate and enter a state termed replicative senescence after a finite number of population doublings in vitro. Presenescent human fibroblasts, when treated with a sub-lethal dose of H2O2, enter long term growth arrest resembling replicative senescence. H2O2 induced growth arrest; p53 protein expression and the effect of vitamin C as an antioxidant were determined in this study.

---

Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.

Produktdetails

• Verlag: LAP Lambert Academic Publishing
• Aufl.
• Seitenzahl: 204
• Erscheinungstermin: 2. Dezember 2011
• Englisch
• Abmessung: 220mm x 150mm x 13mm
• Gewicht: 322g
• ISBN-13: 9783846553268
• ISBN-10: 3846553263
• Artikelnr.: 34692348

Autorenporträt

Name: Sahar Khalil Abdel-Gawad,MD, DHPE.Lecturer of Histology & Cell Biology, Faculty of Medicine, Suez Canal University (FOM/SCU), Egpyt.Has a Diploma Degree in Health Professions Education (DHPE) in 2010 from Suez Canal University (FOM/SCU), Egpyt.