Synthesis of Spirooxindole Fused Nitrochromenes and Styryl-Chromene Synthesis is divided into two chapters.Chapter I describes the Green synthesis of Spirooxindole pyrrolidine / piperidine fused nitrochromene. The new spirocyclic oxindoles were synthesized by a greener method.Chapter II deals with the synthesis of (E)-phenyl-3-styryl-2H-chromene derivatives and studying their biological activities.