Scott Spangler

Accelerating Discovery

Mining Unstructured Information for Hypothesis Generation

• Gebundenes Buch

Produktbeschreibung

This book describes a novel approach to scientific research that uses unstructured data analysis as a generative tool for new hypotheses. The author develops a systematic process for leveraging heterogeneous structured and unstructured data sources, data mining, and computational architectures to make the discovery process faster and more effective. This process accelerates human creativity by allowing scientists and inventors to more readily analyze and comprehend the space of possibilities, compare alternatives, and discover entirely new approaches.

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Produktdetails

• Chapman & Hall/CRC Data Mining and Knowledge Discovery Series
• Verlag: Apple Academic Press Inc.
• Seitenzahl: 270
• Erscheinungstermin: 9. Oktober 2015
• Englisch
• Abmessung: 231mm x 155mm x 18mm
• Gewicht: 624g
• ISBN-13: 9781482239133
• ISBN-10: 1482239132
• Artikelnr.: 42749935

Autorenporträt

Scott Spangler is a principal data scientist, distinguished engineer, and master inventor in the Watson Innovations Group at the IBM Almaden Research Center. He has been involved with knowledge base and data mining research for the past 25 years. His recent work has applied Watson technology to help accelerate cancer research. He holds 45 patents and is the author of over 30 publications. He received a BS in mathematics from MIT and an MS in computer science from the University of Texas.

Inhaltsangabe

Introduction. Why Accelerate Discovery? Form and Function. Exploring
Content to Find Entities. Organization. Relationships. Inference.
Taxonomies. Orthogonal Comparison. Visualizing the Data Plane. Networks.
Examples and Problems. Problem: Discovery of Novel Properties of Known
Entities. Problem: Finding New Treatments for Orphan Diseases from Existing
Drugs. Example: Target Selection Based on Protein Network Analysis.
Example: Gene Expression Analysis for Alternative Indications. Example:
Side Effects. Example: Protein Viscosity Analysis Using Medline Abstracts.
Example: Finding Microbes to Clean Up Oil Spills. Example: Drug
Repurposing. Example: Adverse Events. Example: Discovering New P53 Kinases.
Conclusion and Future Work.