Muhammad Sajid Hamid Akash, Kanwal Rehman, Kanwal Irshad, Shuqing Chen

Pharmaceutical Biotechnology in Drug Development (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Pharmaceutical Biotechnology in Drug Development summarizes key concepts and the latest developments of biotechnology applied to the development of biopharmaceuticals. Chapters present a comprehensive collection of introductory biotechnology technologies and their modern concepts and cover pharmacokinetic and pharmacodynamic behavior of biopharmaceuticals and modification techniques of amino acids and nucleic acid. Other sections focus on topics such as gene therapy, immunological preparations and nanoparticles which are the major contributions of pharmaceutical biotechnology. Final chapters discuss emerging techniques in the field of pharmaceutical biotechnology to meet current patient and health care demand.

This book is an essential reference useful for pharmaceutical scientists, clinicians and academic researchers who want easy access to up-to-date practices of pharmaceutical biotechnology. Corporate researchers will also benefit from this book's succinct and objective content structure.

• Includes key concepts at the foundation of the technology and relevant for protein therapeutics
• Explains how advances in other areas such as genomics, proteomics and high-throughput screening have paved the way for exploring new avenues of drug discovery
• Covers the importance of biotechnology in the development of new biopharmaceuticals, along with their pharmacodynamics and pharmacokinetics

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 236
• Erscheinungstermin: 21. April 2023
• Englisch
• ISBN-13: 9780443191367
• Artikelnr.: 67826588

Autorenporträt

Dr. Akash is currently working as associate professor and chairman at Department of Pharmaceutical Chemistry, Government College University Faisalabad (GCUF), Pakistan. He got his bachelor and master's degrees in pharmacy from Bahauddin Zakariya University Multan, Pakistan and PhD degree in Pharmaceutical Analysis from Zhejiang University, China. Currently, he is focusing on investigating the effect of EDCs on various molecular and metabolic pathways that are involved in metabolic disorders and the treatment strategies of these EDCs-induced metabolic disorders funded by Higher Education Commission (HEC) of Pakistan. His Research work is the cutting edge and worthy of extension in developing countries like Pakistan, where it can be most beneficial and cost-effective especially for diabetic patients. Based on his significant scientific contributions in the field of Pharmaceutical Sciences, he has been awarded "Research Productivity Award from Pakistan Council for Science and Technology (PCST), PAS Gold Medal from Pakistan Academy of Sciences and A.R. Shakoori Gold Medal from Zoological Society of Pakistan.Dr. Kanwal Rehman PhD is working as Associate Professor at Department of Pharmacy in The Women University, Multan, Pakistan. Dr. Kanwal Rehman received her PhD in Pharmacology and Toxicology from Zhejiang University, Hangzhou, China in 2015. She nurtures a keen interest in pathogenesis of metabolic disorders like diabetes mellitus, obesity, and new therapeutic modalities for its treatment. Other work includes detection of environmental pollutants and their cytotoxic effects. She has published about 135 articles. She has also published 50 book chapters with international publishers and 4 books with Springer-Nature. Currently, she is focusing on the investigation of role of pharmacogenomics based upon gene polymorphism on various molecular and metabolic pathways that are involved in mitogenic disorders and treatment strategies like natural biogenic compounds against different risk factors of metabolic disorders including pancreatitis, cardiometabolic disorders and hormonal imbalance. Dr. Kanwal Rehman has also been awarded Research productivity award by Pakistan Council for Science and Technology (PCST), Pakistan.Dr. Kanwal Irshad is working as PhD scholar at Department of Pharmaceutical Chemistry in Government College University Faisalabad, Pakistan. She has done her MPhil from Government College University Faisalabad, Pakistan. She completed her bachelor's (Doctor of Pharmacy) from University of Agriculture, Faisalabad. She has done excellent work on exploring the effect of arsenic on hepatoxicity and nephrotoxicity and their amelioration by bioactive compounds. She has published 5 articles and 8 book chapters with international book publishers. She has received HEC PhD indigenous scholarship for completion of PhD by Higher Education Commission (HEC) of Pakistan. Currently, she is focusing on the investigation of different molecular pathways of arsenic in neurological disorders and their treatment strategies by naturally occurring bioactive compounds.

Inhaltsangabe

1. Introduction to modern concepts in pharmaceutical biotechnology and drug
development
2. Pharmacokinetic and pharmacodynamics of biotechnology products
3. Role of biotechnology in amino acids modification
4. Role of biotechnology in nucleic acid modification
5. Monoclonal antibodies: Development, characterization and therapeutic
application
6. Development of nanoparticles: recent developments and future prospects
7. Production of biopharmaceuticals from genetically modified organisms
8. Metabolomics as bioanalytical approach for pharmaceutical biotechnology
in drug development
9. New biological targets for drug discovery and development
10. Signaling pathways of membrane-spanning receptors for drug discovery
and development