Investigations of chromosomal replication in live E.coli cells

Investigations of chromosomal replication in live E.coli cells

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All living organisms pass on their genetic information to their offspring in the form of DNA or RNA molecules by duplicating them across generations. In the bacteria, their genes are packed in long chains of DNA molecules or chromosomes. One of the widely studied model organisms, Escherichia coli, replicates its circular chromosome in two directions starting from an origin region of chromosome with independent replication complexes or replisomes simultaneously synthesizing the daughter chromosomes. DNA replication is an important process of the E. coli life cycle because of occurrence of small...