Stuart J. Pocock

Clinical Trials

A Practical Approach

• Gebundenes Buch

Produktbeschreibung

This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes the design, analysis, and interpretation of clinical trials in a non-technical manner and provides a general perspective on their historical development, current status, and future strategy. Features examples derived from the author s personal experience.

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Produktdetails

• Verlag: Wiley & Sons
• 1. Auflage
• Seitenzahl: 280
• Erscheinungstermin: 8. Januar 1991
• Englisch
• Abmessung: 235mm x 157mm x 20mm
• Gewicht: 567g
• ISBN-13: 9780471901556
• ISBN-10: 0471901555
• Artikelnr.: 13938125

Autorenporträt

Stuart J. Pocock is a British medical statistician. He has been professor of medical statistics at the London School of Hygiene and Tropical Medicine since 1989. His research interests include statistical methods for the design, monitoring, analysis and reporting of randomized clinical trials.

Inhaltsangabe

Introduction: The Rationale of Clinical Trials.
The Historical Development of Clinical Trials.
Organization and Planning.
The Justificaton for Randomized Controlled Trials.
Methods of Randomization.
Blinding and Placebos.
Ethical Issues.
Crossover Trials.
The Size of a Clinical Trial.
Monitoring Trial Progress.
Forms and Data Management.
Protocol Deviations.
Basic Principles of Statistical Analysis.
Further Aspects of Data Analysis.
Publication and Interpretation of Findings.
References.
Index.