Periodontal pockets are favorable area within the gums created by periodontopathic pathogens where access to routine cleaning are difficult leading to destruction of soft tissues supporting teeth and clinical attachment. Even though mechanical debridement removes plaque which contains microorganisms,it's impossible to completely eradicate all virulence factors; therefore, antibacterial therapy is recommended as supplementary measure. In conjunction with scaling and root planing, the adjunctive use of local drug delivery may enhance the results in sites that don't respond to conventional therapy. Local drug delivery systems with controlled release properties have the potential to be used as a therapeutic component in the management of periodontal diseases.