Molecular Hybridization: A revolution in contemporary drug development
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Over the last few years, the use of hybrid molecules has increased exponentially in developing new drugs. In comparison to the use of cocktail of drugs, the hybrid molecules provide the advantage of combining together the pharmacophores of two or more drugs and thereby result into the improvement in the medicinal profile of the molecule. This book provides an overview of the hybrid molecules that have been successfully developed for targeting fungal, tubercular, malarial, inflammatory and cancer diseases. Each of the categories of diseases has been discussed separately. The account of hybrid m...
Over the last few years, the use of hybrid molecules has increased exponentially in developing new drugs. In comparison to the use of cocktail of drugs, the hybrid molecules provide the advantage of combining together the pharmacophores of two or more drugs and thereby result into the improvement in the medicinal profile of the molecule. This book provides an overview of the hybrid molecules that have been successfully developed for targeting fungal, tubercular, malarial, inflammatory and cancer diseases. Each of the categories of diseases has been discussed separately. The account of hybrid molecules developed against these diseases by the combination of natural products and synthetic molecules is given under different headings. The analysis should help shed light on the exciting field of molecular hybridization and may prove useful for the development of new drugs.
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