Andere Kunden interessierten sich auch für
![Nanomaterials for Tumor Targeting Theranostics: A Proactive Clinical Perspective]( "Nanomaterials for Tumor Targeting Theranostics: A Proactive Clinical Perspective")
Nanomaterials for Tumor Targeting Theranostics: A Proactive Clinical Perspective169,99 €![Cancer Therapeutics and Imaging: Molecular and Cellular Engineering and Nanobiomedicine]( "Cancer Therapeutics and Imaging: Molecular and Cellular Engineering and Nanobiomedicine")
Cancer Therapeutics and Imaging: Molecular and Cellular Engineering and Nanobiomedicine171,99 €![Silica Nanoparticles as Drug Delivery System for Immunomodulator Gmdp]( "Silica Nanoparticles as Drug Delivery System for Immunomodulator Gmdp")
Silica Nanoparticles as Drug Delivery System for Immunomodulator Gmdp99,99 €![Quantum in: Brain -Teleportation of Bacteria]( "Quantum in: Brain -Teleportation of Bacteria")
Quantum in: Brain -Teleportation of Bacteria39,99 €![Nanotechnology in Water Treatment Applications]( "Nanotechnology in Water Treatment Applications")
Nanotechnology in Water Treatment Applications262,99 €![Designing Hybrid Nanoparticles]( "Designing Hybrid Nanoparticles")
Designing Hybrid Nanoparticles126,99 €![Nanoparticles and Nanomaterials: Designs, Characterization and Applications]( "Nanoparticles and Nanomaterials: Designs, Characterization and Applications")
Nanoparticles and Nanomaterials: Designs, Characterization and Applications150,99 €
Despite progresses in surgery, radiotherapy, and in chemotherapy, an effective curative treatment of gliomas does not yet exist. Mortality is still close to 100% and the average survival of patients with GBM is less than 1 year. The efficacy of current anti-cancer strategies in brain tumors is limited by the lack of specific therapies against malignant cells. Besides, the delivery of the drugs to brain tumors is limited by the presence of the blood brain barrier. The oncogenesis of gliomas is characterized by several biological processes and genetic alterations, involved in the neoplastic transformation. The modulation of gene expression to more levels, such as DNA, mRNA, proteins and transduction signal pathways, may be the most effective modality to down-regulate or silence some specific gene functions. Gliomas are characterized by extensive microvascular proliferation and a higher degree of vasculature. In malignant gliomas targeted therapies efficacy is low.