Pathophysiology of wound healing

Pathophysiology of wound healing

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Normal wound healing involves a complex and dynamic but superbly orchestrated series of events leading to the repair of injured tissues. Acute wounds normally heal in a very orderly and efficient manner characterized by four distinct, but overlapping phases: hemostasis, inflammation, proliferation and remodelling. Specific biological markers characterize healing of acute wounds. Likewise, unique biologic markers also characterize pathologic responses resulting in fibrosis and chronic non-healing ulcers. As we continue to develop new information about the unique biological markers associated wi...