Psoriasis is a serious, chronic, non-communicable autoimmune disease affecting million of the population worldwide. It is characterized by the development of whitish scaly, indurated, demarcated erythematous plaque. Psoriasis is not only limited to the skin but also involves joints and nails. Clinically Ps is classified into two types Pustular and Non-pustular psoriasis. Psoriasis vulgaris and Generalized Pustular Psoriasis are the most common effects worldwide. Psoriasis is a chronic recurrent disease that demands long-term therapy. Corticosteroids, retinoids, and biologics such as TNF-alpha inhibitors, Il-17 Inhibitors, and Il-23 inhibitors are used in the long-term management of psoriasis.