In MOFs, the metal ions and ligands {called Primary Building Units (PBUs)} assemble together to form molecular structural units {called Secondary Building Units (SBUs)}. A number of SBUs further join together via covalent and non covalent interactions to generate the MOF structures. MOFs find several applications in the field such as gas storage, gas purification, gas separation, catalysis, nonlinear optics, magnetism and also in biotechnology. The entire work has been divided into seven chapters. In the first chapter, the basic introduction of metal organic frameworks (MOFs) including their synthetic methods, structural features and potential applications has been discussed in brief, followed by literature review on the subject has been taken up in great detail in which work carried out by other research groups with respect to synthesis of MOFs with pseudohalides and nicotinamide as ligands has been discussed. In chapter three, four, five, six, seven synthesis and characterization of metal organic framework compounds using several metal ions have been presented.