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The work is a 'one-stop' text for trainees and consultants in Endocrinology and Diabetes, residents, those preparing for sub-specialty exams and other professionals allied to the area who need to gain an understanding of the field. It acts as both a point of reference for the experienced consultant as well as a trusted training resource.
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The work is a 'one-stop' text for trainees and consultants in Endocrinology and Diabetes, residents, those preparing for sub-specialty exams and other professionals allied to the area who need to gain an understanding of the field. It acts as both a point of reference for the experienced consultant as well as a trusted training resource.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Produktdetails
- Produktdetails
- Verlag: Hurst & Co.
- 3rd edition
- Seitenzahl: 2656
- Erscheinungstermin: 22. Juni 2022
- Englisch
- Abmessung: 286mm x 232mm x 86mm
- Gewicht: 5634g
- ISBN-13: 9780198870197
- ISBN-10: 0198870191
- Artikelnr.: 61605178
- Verlag: Hurst & Co.
- 3rd edition
- Seitenzahl: 2656
- Erscheinungstermin: 22. Juni 2022
- Englisch
- Abmessung: 286mm x 232mm x 86mm
- Gewicht: 5634g
- ISBN-13: 9780198870197
- ISBN-10: 0198870191
- Artikelnr.: 61605178
Professor Wass is a Professor of Endocrinology at Oxford University and was the Head of the Department of Endocrinology at the Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital Oxford, UK until 2011. From 1989 he was Professor of Clinical Endocrinology and Sub-Dean, University of London at Bart's. He founded and ran the Oxfordshire Osteoporosis Service in 1995. John Wass is currently the Clinical Reference Group Chair for Endocrinology in the UK. He was President of the European Federation of Endocrine Societies from 2001-2203 and was Chairman of the Society for Endocrinology (2006-2009). He was awarded the Distinguished Physician of the Year Award by the American Endocrine Society, the first non-American to ever receive this award Elected Academic Vice President of the Royal College of Physicians London in 2012 he has chaired the Royal College of Physicians Working Party 'Action on Obesity: Comprehensive Care for All' published in January 2013. Wiebke Arlt qualified at the University of Cologne in 1990. She trained in Endocrinology from 1994 to 1998 under the auspices of Professor Bruno Allolio at the University Hospital Würzburg, Germany. She then spent two years in the Molecular Endocrinology Lab of the Department of Paediatrics at the University of California in San Francisco (UCSF), hosted by Walter Miller. Following her return to Wuerzburg in 2001 she was appointed Consultant Endocrinologist. She obtained a prestigious Heisenberg Fellowship from the German Research Council and moved to Birmingham in October 2002. In 2004, she obtained an MRC Senior Clinical Fellowship and was appointed Senior Lecturer at the University of Birmingham. Promotion to Chair of Medicine in 2006 and to Head of the Centre for Endocrinology, Diabetes and Metabolism in 2008. She was awarded the William Withering Chair of Medicine in 2014 and appointed as Director of the newly founded Institute of Metabolism and Systems Research in 2015. Professor Semple is an endocrinologist based at the University of Edinburgh, where he is also Dean of Postgraduate Research for the College of Medicine and Veterinary Medicine. His interests include insulin resistance, diabetes, hypoglycaemia and mosaic growth disorders, in each of which he engages in fundamental molecular and cellular research, translational studies, and clinical practice.
1. 1. Principles of basic and clinical endocrinology
2. 1.1: Lynn Loriaux: Endocrine Practice Fundamentals
3. 1.2: John W. Funder: Hormones and receptors: fundamental considerations
4. 1.3: Ken Siddle and Gemma Brierley: Molecular aspects of hormonal
regulation
5. 1.4: Janine A. Danks and Samantha J. Richardson: Endocrinology and
evolution: lessons from comparative endocrinology
6. 1.5: James Gibney, Indi Banerjee, and Ken Ho: Hormones Across the Lifespan
7. 1.6: Brian Keevil, Peter Trainer, and William Drake: Pituitary assessment
strategy
8. 1.7: Simon Pearce and Catherine Owen: Endocrine autoimmunity
9. 1.8: Jerome Bertherat, Anne Jouinot, and Fidéline Bonnet-Serrano: Common
Features of Endocrine Tumours
10. 1.9: Trevor Cole: Genetic Aspects of Endocrine Disease
11. 1.10: George Mastorakos, Markella Nezi, Djuro Macut, and Maria Papagianni:
Environmental Influences on Endocrine Disease
12. 1.11: Georg Brabant and H. Oster: Endocrinology, sleep and circadian
rhythms
13. 1.12: Richard Ross: Principles of Hormone replacement
14. 1.13: Jonathan Valabhji and Rochan Agha-Jaffar: Prevention in endocrinology
15. 2. Pituitary and hypothalamic diseases
16. 2.1: John Morris: Functional anatomy of the hypothalamus and pituitary
17. 2.2: Stephen G. Ball: The neurohypophysis
18. 2.3: Aetiology, pathogenesis, and management of disease of the pituitary
19. 2.3.1: Mehul T. Dattani and Louise C. Gregory: Development of the pituitary
and genetic forms of hypopituitarism
20. 2.3.2: Shlomo Melmed: Molecular pathogenesis of pituitary tumours
21. 2.3.3: Luis Syro, Kalman Kovacs, and Fabio Rotondo: Histopathology of
pituitary tumours
22. 2.3.4: Jean-Francois Bonneville, Sonia Nagi, and Iulia Potorac: Imaging of
the pituitary
23. 2.3.5: Miles J. Levy, Ragini Bhake, and Narendra Reddy: Hypopituitarism:
replacement of adrenal, thyroid, and gonadal axes
24. 2.3.6: Jens Jørgensen: Adult growth hormone deficiency
25. 2.3.7: Edward R. Laws Jr, David L. Penn, and Caroline S. Repetti: Surgery
of pituitary tumours
26. 2.3.8: Naomi Fersht and Francesca Solda: Pituitary radiotherapy
27. 2.3.9: Nicholas Tritos and Anne Klibanski: Prolactinomas and
hyperprolactinaemia (including macroprolactinaemia)
28. 2.3.10: John Wass, Peter J. Trainer, and Márta Korbonits: Acromegaly
29. 2.3.11: Nienke Biermasz and Wouter R. van Furth: Clinically nonfunctioning
pituitary tumours and gonadotropinomas
30. 2.3.12: Mark Gurnell, Olympia Koulouri, and Waiel Bashari: Thyrotropinomas
31. 2.3.13: Ann McCormack: Pituitary carcinoma
32. 2.3.14: Niki Karavitaki, Shu Teng Chai, and Shahzada Ahmed: Pituitary
incidentalomas
33. 2.4: Aetiology, pathogenesis, and management of diseases of the
hypothalamus
34. 2.4.1: Mehul Dattani, Hoong-Wei Gan, and Manuela Cerbone: Hypothalamic
dysfunction (hypothalamic syndromes)
35. 2.4.2: Niki Karavitaki: Craniopharyngiomas
36. 2.4.3: Jürgen Honegger, Ulrike Ernemann, and Rudi Beschorner: Perisellar
tumours including cysts, hamartomas, and vascular tumours
37. 2.4.4: Mark E. Molitch and Jelena Kravarusic: Lymphocytic hypophysitis and
other inflammatory conditions of the pituitary
38. 2.5: Susan M Webb, Anna Aulinas, Cristina Colom, and José Barahona: Pineal
physiology and pathophysiology, including pineal tumours
39. 3. The Thyroid
40. 3.1: Evaluation of the thyroid patient
41. 3.1.1: Robert Volpé and Clark Sawin: The history and iconography relating
to the thyroid gland
42. 3.1.2: W. Edward Visser: Biosynthesis, transport, metabolism, and actions
of thyroid hormones
43. 3.1.3: Inge Bülow Pedersen and Stig Andersen: Clinical assessment of the
thyroid patient
44. 3.1.4: Ulla Feldt-Rasmussen: Thyroid function tests and the effects of
drugs
45. 3.1.5: Robin P. Peeters and Anita Boelen: Nonthyroidal illness syndrome
46. 3.1.6: Steen Bonnema and Laszlo Hegedüs: Thyroid imaging: nuclear medicine
techniques
47. 3.1.7: Laszlo Hegedüs and Finn N. Bennedbæk: Thyroid imaging: nonisotopic
techniques
48. 3.1.8: Mark P. J. Vanderpump: Epidemiology of thyroid disease and swelling
49. 3.2: Aetiology of thyroid disorders
50. 3.2.1: Terry Davies, Francesca Menconi, and Yaron Tomer: The complex
genetics of thyroid disease
51. 3.2.2: Josef Köhrle: Environmental factors
52. 3.2.3: Michael B. Zimmermann: Iodine deficiency disorders
53. 3.2.4: Shunichi Yamashita, Furio Pacini, and Rossella Elisei:
Radiation-induced thyroid disease
54. 3.2.5: Anthony P. Weetman: Autoimmune thyroid disease
55. 3.2.6: Elizabeth N. Pearce and Alan Farwell: Thyroiditis
56. 3.3: Thyrotoxicosis and related disorders
57. 3.3.1: Claudio Marcocci and Filomena Cetani: Clinical assessment and
systemic manifestations of thyrotoxicosis
58. 3.3.2: Annie W. C. Kung and C.L. Cheung: Thyrotoxic periodic paralysis
59. 3.3.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Thyrotoxic storm
60. 3.3.4: Simon Pearce: Subclinical hyperthyroidism
61. 3.3.5: Francesco Latrofa and Paolo Vitti: Causes and laboratory
investigations of thyrotoxicosis
62. 3.3.6: Luigi Bartalena: Anti-thyroid drug treatment for thyrotoxicosis
63. 3.3.7: Markus Luster and Michael Lassmann: Radio-iodine treatment of
hyperthyroidism
64. 3.3.8: Nancy Dugal Perrier, Orlo Clark, and Sarah B. Fisher: Surgery for
thyrotoxicosis
65. 3.3.9: Jacques Orgiazzi: Management of Graves hyperthyroidism
66. 3.3.10: Wilmar M. Wiersinga: Graves orbitopathy and dermopathy
67. 3.3.11: Dagmar Führer and Holger Jäschke: Management of toxic multinodular
goitre and toxic adenoma
68. 3.3.12: Wilmar M. Wiersinga: Management of thyrotoxicosis without
hyperthyroidism
69. 3.4: Hypothyroidism
70. 3.4.1: Massimo Tonacchera and Luca Chiovato: Clinical assessment and
systemic manifestations of hypothyroidism
71. 3.4.2: Ferruccio Santini: Causes and laboratory investigation of
hypothyroidism
72. 3.4.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Myxoedema coma
73. 3.4.4: Bijay Vaidya and Chantal Daumerie: Subclinical hypothyroidism
74. 3.4.5: Mark Gurnell, Carla Moran, and V. K. Chatterjee: Syndromes of
Resistance to Thyroid Hormone
75. 3.4.6: Birte Nygaard: Treatment of hypothyroidism
76. 3.5: Thyroid lumps
77. 3.5.1: Dagmar Führer and Holger Jäschke: Pathogenesis of nontoxic goitre
78. 3.5.2: Hans Graf and Gilberto Paz Filho: Management of nontoxic
multinodular goitre
79. 3.5.3: Laszlo Hegedüs and Finn N. Bennedbæk: Management of the single
thyroid nodule
80. 3.5.4: Massimo Santoro, Barbara Jarzab, Jolanta Krajewska, and Dagmara
Rusinek: Pathogenesis of thyroid cancer
81. 3.5.5: Fulvio Basolo and Clara Ugolini: Pathology of thyroid cancer
82. 3.5.6: Corin Badiu and Ruxandra Dobrescu: Papillary, follicular, and
anaplastic thyroid carcinoma and lymphoma
83. 3.5.7: Friedhelm Raue and Karin Frank-Raue: Medullary thyroid carcinoma
84. 4. Parathyroid, calcium, and bone metabolism
85. 4.1: David Goltzman and Geoffrey N. Hendy: Parathyroid anatomy, hormone
synthesis, secretion, action, and receptors
86. 4.2: Claudio Marcocci, Federica Saponaro, and Filomena Cetani:
Hypercalcaemia
87. 4.3: John P. Bilezikian: Primary hyperparathyroidism
88. 4.4: Dolores Shoback and Muriel Babey: Familial Hypocalciuric Hypercalcemia
Types 1-3 and Neonatal Severe Primary Hyperparathyroidism
89. 4.5: Rajesh Thakker, Bart Clarke, and Fadil M. Hannan: Hypocalcaemic
disorders, hypoparathyroidism, and pseudohypoparathyroidism
90. 4.6: Paul D. Miller and Michael Pazianas: Bones and the Kidney-The
Practical Conundrum: Distinguishing Between Osteoporosis and the Bone
Diseases that Accompany Chronic Renal Failure
91. 4.7: Laleh Ardeshirpour, Thomas O. Carpenter, and Cemre Robinson:
Hypercalcaemic and hypocalcaemic syndromes in children
92. 4.8: Richard Eastell: Osteoporosis
93. 4.9: Graham R. Williams, J. H. Duncan Bassett, Bernard Freudenthal, and
Laura M. Watts: Thyroid disorders and bone disease
94. 4.10: Socrates E. Papapoulos: Paget s disease of bone
95. 4.11: Michael P. Whyte: Rickets and osteomalacia (acquired and heritable
forms)
96. 4.12: Gherardo Mazziotti, Ernesto Canalis, and John P. Bilezikian:
Glucocorticoid-induced osteoporosis
97. 5. The adrenal gland and endocrine hypertension
98. 5.1: Peter Guest: Adrenal imaging
99. 5.2: Fausto Palazzo and Radu Mihai: Adrenal surgery
100. 5.3: Irina Bancos, Massimo Terzolo, and Wiebke Arlt: Adrenal incidentaloma
101. 5.4: Jérôme Bertherat, Rossella Libè, and Anne Jouinot: Adrenocortical
cancer
102. 5.5.1: Eamonn R. Maher and Ruth T Casey: Genetics of phaeochromocytomas,
paragangliomas, and neuroblastoma
103. 5.5.2: Henri Timmers: Management of phaeochromocytoma and paragagnlioma
104. 5.6.1: Maria Christina Zennaro, Fabio Fernandes-Rosa, and Sheerazed
Boulkroun: Genetics of primary aldosteronism and other steroid-related
causes of endocrine hypertension
105. 5.6.2: Morris Brown and Will Drake: Management of primary aldosteronism
106. 5.7: John Newell-Price: Cushing s syndrome
107. 5.8.1: Li Chan and Shwetha Ramachandrappa: Genetics of Adrenal
Insufficiency
108. 5.8.2: Wiebke Arlt: Management of Adrenal Insufficiency
109. 5.9.1: Nils P. Krone: Genetics of congenital adrenal hyperplasia
110. 5.9.2: Richard J. Auchus: Modern management of congenital adrenal
hyperplasia and prospects for the future
111. 6. Neuroendocrine tumours and genetic disorders
112. 6.1: Guido Rindi and Rajaventhan Srirajaskanthan: Overview and
Pathophysiology of Neuroendocrine Neoplasms
113. 6.2: Whaljit Dhillo and Paul Bech: Neuroendocrine tumour markers
114. 6.3: Rajaventhan Srirajaskanthan, Martyn E. Caplin, and Dominique Clement:
Carcinoid syndrome
115. 6.4.1: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor: Lung
neuroendocrine tumours
116. 6.4.2: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor:
Non-functioning pancreatic neuroendocrine tumours
117. 6.5: Christos Toumpanakis and Martyn E. Caplin: Gastrinoma
118. 6.6: Ashley Grossman and Ingrid YF Mak: Insulinoma and hypoglycaemia
119. 6.7: Karim Meeran: Glucagonoma
120. 6.8: Alia Munir: Vasointestinal Polypeptide Secreting Tumours
121. 6.9: John Wass: Somatostatinoma
122. 6.10: Prakash Manoharan: Imaging neuroendocrine tumours of the
gastrointestinal tract/gastroenteropancreatic neuroendocrine tumours
(GEP-NET)
123. 6.11: Rajesh V. Thakker: Multiple endocrine neoplasia type 1
124. 6.12: Electron Kebebew, Douglas Wiseman, and Mustapha El Lakis: Multiple
endocrine neoplasia type 2a and 2b
125. 6.13: Eamonn R. Maher and Ruth T. Casey: Familial syndromes and genetic
causes of paraganglioma and phaeochromocytoma
126. 6.14: Constantine A. Stratakis and Fabio Faucz: Carney s complex
127. 6.15: Michael A. Levine and Steven A. Lietman: Molecular and Clinical
Characteristics Of the McCune-Albright Syndrome
128. 6.16: Charis Eng, Lamis Yehia, and Shreya Malhotra: Cowden syndrome
129. 7. Growth and development during childhood and adolescence
130. 7.1: Growth and its Disorders
131. 7.1.1: Gary Butler: Recognising Normal and Disordered Growth
132. 7.1.2: Alexander A. L. Jorge, Fernanda A. Correa, and Renata C. Scalco:
Disorders of the GH-IGF Axis
133. 7.1.3: Anita Hokken-Koelega: Short stature in children born small for
gestational age
134. 7.1.4: Steve Chernausek and Minu George: Growth Disorders with no defined
aetiology
135. 7.1.5: Lars Savendahl and Emelie Benji: Tall Stature
136. 7.2: Sex Development
137. 7.2.1: Olaf Hiort and Ralf Werner: Sex Determination and Differentiation
138. 7.2.2: S. Faisal Ahmed and Salma R. Ali: Disorders of Sex Development (DSD)
in the newborn
139. 7.2.3: Alan Rogol and John Fuqua: Recognising Normal and Disordered
Pubertal Development
140. 7.2.4: Alan Rogol and John Fuqua: Pubertal Delay and Hypogonadism
141. 7.2.5: Julianne Leger and Jean-Claude Carel: Precocious Puberty
142. 7.3: Helena Gleeson and Rohana Wright: Transition In Endocrinology
143. 8. Female endocrinology and pregnancy
144. 8.1: Normal female endocrinology and ovarian disorders
145. 8.1.1: Chris McCartney and John Marshall: Neuroendocrinology of
reproduction: the role of hypothalamus and pituitary
146. 8.1.2: Terhi Piltonen and Juha Tapanainen: Ovarian and uterine development
from fetal life to puberty
147. 8.1.3: Gurkan Bozdag, Baris Ata, and Engin Türkgeldi: Menstrual cycle and
ovulation
148. 8.2: Evaluation of the female patient with suspected reproductive endocrine
disorders
149. 8.2.1: Channa Jayasena, Steve Franks, and Rachel Roberts: Clinical
evaluation of patient with suspected reproductive endocrine disorders
150. 8.2.2: Daniel Dumesic and Zain Al-Safi: Laboratory evaluation
151. 8.3: Reproductive endocrine disorders
152. 8.3.1: Sarah L. Berga: Disorders of gonadotrophin secreton
153. 8.3.2: Julian R. E. Davis and Agnieszka Swiecicka: Hyperprolactinaemia
154. 8.3.3: Deepthi Lavu, Radha Indusekhar, and Shaughn O'Brien: Premenstrual
syndrome
155. 8.4: Polycystic ovary syndrome and other androgen excess disorders
156. 8.4.1: Bulent Yildiz and Sezcan Mumusoglu: Polycystic ovary syndrome:
definitions, phenotypes, prevalence and genetics
157. 8.4.2: R Jeffrey Chang: Polycystic ovary syndrome: reproductive aspects
158. 8.4.3: David Ehrmann and Susan Sam: Polycystic ovary syndrome: metabolic
aspects
159. 8.4.4: Duarte Pignatelli, Ricardo Azziz, and Bulent Yildiz: Polycystic
ovary syndrome: Hirsutism
160. 8.5: Female hypogonadism and menopause
161. 8.5.1: Ephia Yasmin and Gerard S. Conway: Female hypogonadism: premature
ovarian insufficiency
162. 8.5.2: Dimitrios G. Goulis, Stavroula A. Paschou, and Panagiotis
Anagnostis: Female hypogonadism: Endocrinology of the menopause and hormone
replacement therapy
163. 8.6: Female infertility
164. 8.6.1: Adam Balen and Susie Jacob: Female Infertility and assisted
reproduction
165. 8.6.2: Kutluk Oktay and Enes Taylan: Female infertility: fertility
preservation
166. 8.7: Hormonal contraception
167. 8.7.1: Jennifer Chin Bliss Kaneshiro: Hormonal contraception
168. 8.8: Exogenous factors and female repoductive health
169. 8.8.1: Alessandra Gambineri and Daniela Ibarra-Gasparini: Exogenous factors
and female reproductive health: common extragonadal endocrinopathies
affecting reproduction
170. 8.8.2: Siew Lim, Aya Mousa, Soulmaz Shorakae, and Lisa Moran: Exogenous
factors and female reproductive health: nutrition and reproduction
171. 8.8.3: Evy Diamanti-Kandarakis and Eleni A Kandaraki: Exogenous factors and
female reproductive health: envrionment and reproduction
172. 9. Endocrinology of pregnancy
173. 9.1: Endocrine disorders of Pregnancy
174. 9.1.1: Peter Taylor, LDKE Premawardhana, and John Lazarus: General
considerations relating to thyroid disease in pregnancy
175. 9.1.2: Kris Poppe, Flora Veltri, and David Unuane: Management of thyroid
disorders before assisted and spontaneous pregnancy
176. 9.1.3: Tim Korevaar and Robin Peeters: Thyroid disease during pregnancy
177. 9.1.4: Nobuyuki Amino and Naoko Arata: Management of thyroid disorders
after pregnancy
178. 9.1.5: A. S. Paul van Trotsenburg Nitash and Zwaveling-Soonawala: Thyroid
disorders in newborns, infants and children
179. 9.1.6: Mark Molitch and Wenyu Huang: Pituitary tumours in pregnancy
180. 9.1.7: Paul Carroll, Niki Karavitaki, and Kirstie Lithgow: Other disorders
of the pituitary and hypothalamus in pregnancy
181. 9.1.8: David Torpy, Michael O'Reilly, and Sunita De Sousa: Adrenal disease
in pregnancy
182. 9.1.9: Jeremy Cox and Stephen Robinson: Endocrine bone disease in pregnancy
183. 9.1.10: Sandra Lowe: Imaging of endocrine disorders in pregnancy
184. 10. Male Reproductive Endocrinology
185. 10.1: Normal male reproductive endocrinology
186. 10.1.1: Ilpo Huhtaniemi and Jorma Toppari: Endocrine and local regulation
of testicular hormone and sperm production
187. 10.1.2: Dirk Vanderschueren, Leen Antonio, Nari Kim, and Frank Claessens:
Sex steroid actions in the Male
188. 10.2: Evaluation of the male patient with suspected hypogonadism and/or
infertility
189. 10.2.1: Bradley Anawalt: Clinical evaluation
190. 10.2.2: Jean-Marc Kaufman: Endocrine evaluation
191. 10.2.3: Jackson Kirkman-Brown and Sarah J Conner: Diagnostic Semen analysis
192. 10.3: Male reproductive endocrine disorders
193. 10.3.1: Claus H. Gravholt: Klinefelter s syndrome
194. 10.3.2: Adult Hypogonadism: Aetiology
195. 10.3.2.1: Alvin Matsumoto and Radhika Narla: Etiology of Hypogonadism
196. 10.3.2.2: Giovanni Corona, Mario Maggi, and Giulia Rastrelli: Types of
Treatments
197. 10.3.2.3: Michael Zitzmann: Gonadotrophin induction of spermatogenesis
198. 10.3.2.4: Shehzad Basaria and Thiago Gagliano-Juca: Male Hypogonadism:
Benefits of Testosterone Treatment
199. 10.3.2.5: Adrian Dobs and Swaytha Yalamanchi: Risks of T Treatment
200. 10.3.3: Herman J. Tournaye and Biljana Popovic-Todorovic: Management of
Idiopathic male infertility
201. 10.3.4: Mathis Grossmann, B. Yeap, and Gary Wittert:
Hypothalamo-pituitary-testicular axis fucntion in systemic diseases and
effects of medications
202. 10.3.5: Vincenzo Rochira, Antonio R. M. Granata, and Cesare Carani:
Management of sexual dysfunction
203. 10.3.6: Stephanie Page and Maritza Farrant: Hormonal male contraception
204. 10.3.7: Glenn Braunstein: Gynaecomastia
205. 10.4: Exogenous factors and male reproductive health
206. 10.4.1: Jorma Toppari: Environmental influences on male reproductive health
207. 10.4.2: David Handelsman: Androgen Misuse and Abuse
208. 11. Management of the Transgender Patient
209. 11.1: Jon Arcelus and Walter Bouman: Introduction to Transgender and Gender
Diverse People
210. 11.2: Daniel Klink: Endocrine Treatment of Transgender Youth
211. 11.3: Vin Tangpricha and Craig Sineath: Hormone Therapy in transgender
women
212. 11.4: Guy T'Sjoen and Justine Defreyne: Hormone therapy in transgender men
213. 11.5: Chloë De Roo and Guy T'Sjoen: Fertility Options for Transgender
Persons
214. 12. Endocrine Responses to Systemic Diseases or Substance Use
215. 12.1: Endocrinology of systemic disease
216. 12.1.1: David Henley, Thomas Upton, and Stafford L. Lightman: The endocrine
response to stress
217. 12.1.2: Greet Van den Berghe and Lies Langouche: Endocrinology in the
critically ill
218. 12.1.3: David Johnson, Melissa Nataatmadja, and Yeoungjee Cho: Hormones and
the kidney
219. 12.1.4: Jacob George and Mohammed Eslam: The endocrinology of liver disease
220. 12.1.5: Steven K. Grinspoon and Takara Stanley: Endocrine abnormalities in
HIV infection
221. 12.1.6: Karen Miller: The endocrinology of anorexia nervosa
222. 12.2: Endocrine Complications of Substance Misuse
223. 12.2.1: Marc Walter and Margit Proescholdt: Endocrinology and alcohol
224. 12.2.2: Peter Sonksen and Richard Holt: Use and abuse of
performance-enhancing hormones in sport
225. 12.2.3: Ashley Grossman, Eleni Armeni, and Bernard Khoo: Effect of Opioids
on Adrenal and Reproductive Endocrinology
226. 13. Endocrinology of cancer
227. 13.1: Endocrine Disorders Caused by Cancer or its Treatment
228. 13.1.1: Thomas Papathomas and Vania Nose: Metastatic Disease in Endocrine
Organs
229. 13.1.2: David W. Ray: Paraneoplastic endocrine syndromes
230. 13.1.3: Claire Higham and Rob Murray: Long-term endocrine sequelae of
cancer therapy
231. 13.1.4: Carla Moran: Endocrine complications of biological cancer therapies
232. 13.2: Hormonal therapy for breast and prostatic cancers
233. 13.2.1: Rob Clarke and Alice Greenhalgh: The breast: lactation and breast
cancer as an endocrine disease
234. 13.2.2: Amna Sheri and Laura Morrison: Endocrine treatment of breast cancer
235. 13.2.3: Irina A. Vasilevskaya, Matthew J. Schiewer, and Karen E. Knudsen:
Hormonal Therapy for Prostate Cancer: Molecular basis of efficacy and
therapeutic bypass
236. 14. Obesity, lipids, and metabolic disorders
237. 14.1: Obesity
238. 14.1.1: Anthony Coll: The Physiology of Bodyweight Regulation
239. 14.1.2: Adrian Bauman: Obesity as a Public Health Problem
240. 14.1.3: Rachel Batterham and Friedrich Jassil: Medical Complications of
Obesity
241. 14.1.4: John Wilding and Jonathan Lim: Dietary and Medical Management of
Obesity
242. 14.1.5: Francesco Rubino, Vivian Anastasiou, Luca Ferraro, Dalal Qanaq, and
Ghassan Chamseddine: Metabolic Surgery
243. 14.1.6: Sadaf Farooqi: Assessment of Obesity in Children
244. 14.1.7: Russell Viner and Billy White: Management of Obesity in Children
and Young People
245. 14.1.8: Nick Finer: Planning obesity care pathways
246. 14.2: Lipoprotein metabolism and dyslipidaemia
247. 14.2.1: Bo Angelin and Paolo Parini: Lipoprotein metabolism
248. 14.2.2: Stefano Romeo, Bo Angelin, and Paolo Parini: Genetic forms of
dyslipidaemia
249. 14.3: Other metabolic disorders
250. 14.3.1: Khalid Hussain and Sonya Galcheva: Hyperinsulinaemic Hypoglycaemia
251. 14.3.2: Phillip Gorden and Noemi Malandrino: Autoimmune Hypoglycaemia
252. 14.3.3: Robin H. Lachmann: Disorders of carbohydrate metabolism
253. 14.3.4: Yves Deugnier and Edouard Bardou-Jacquet: Haemochromatosis And
Other Inherited Diseases Of Iron Metabolism
254. 14.3.5: Michael N. Badminton and Danja Schulenburg-Brand: The porphyrias
255. 15. Diabetes mellitus
256. 15.1: Introduction to Diabetes Mellitus
257. 15.1.1: Shanta Persaud and Peter Jones: Physiology of glucose homeostasis
258. 15.1.2: Stephen Colagiuri and Crystal Man Ying Lee: Classification and
diagnosis of diabetes mellitus
259. 15.2: Aetiopathogenesis and Diagnosis of Type 1 Diabetes
260. 15.2.1: Elizabeth J. Mayer-Davis and Daria Igudesman: Epidemiology and
Public Health
261. 15.2.2: Augustin Brooks: Presentation and Natural History
262. 15.2.3: Richard Oram, Susan Wong, and Ayat Bashir: Pathogenesis
263. 15.3: Aetiopathogenesis and Diagnosis of Type 2 Diabetes
264. 15.3.1: Sarah Wild and Jackie Price: Epidemiology and Public Health
265. 15.3.2: Roy Taylor: Presentation and Natural History
266. 15.3.3: Mark Walker, Xuefei Yu, and Amalia Gastaldelli: Pathogenesis
267. 15.4: Non Type 1, Non Type 2 Diabetes
268. 15.4.1: Katherine Owen: Diagnosis of non type 1, non type 2 forms of
diabetes
269. 15.5: Principles of Management of Diabetes
270. 15.5.1: Simon Heller and Jackie Elliott: Structured Education
271. 15.5.2: John Pickup and Nick Oliver: Glucose Monitoring and Sensing
272. 15.5.3: Pratik Choudhary and Peter Jacob: Insulins and insulin delivery
devices
273. 15.5.4: Clifford Bailey and Melanie Davies: Non-insulin glucose lowering
agents
274. 15.5.5: Stephanie Amiel: Hypoglycaemia in the treatment of diabetes
mellitus
275. 15.6: Evidence-based Management of Type 1 Diabetes
276. 15.6.1: Peter Hammond and Fiona Campbell: Strategies for management of type
1 diabetes
277. 15.6.2: Christel Hendrieckx and Jane Speight: Psychological and Behavioural
Aspects of Type 1 Diabetes Management
278. 15.6.3: Colin Dayan and Danijela Tatovic: Immunotherapy for type 1 diabetes
279. 15.6.4: Peter Senior, Martin Drage, Anneliese Flatt, and Chris Callaghan:
Transplantation (islet and solid organ)
280. 15.7: Evidence-based Prevention and Management of Type 2 Diabetes
281. 15.7.1: Peter Winocour and Sagen Zac-Varghese: Strategies for management of
type 2 diabetes
282. 15.7.2: Jane Speight and Tim Skinner: Psychological and Behavioural Aspects
of Type 2 Diabetes Management
283. 15.7.3: Kamiesh Khunti and Nitin Narayan Gholap: Type 2 diabetes in
different ethnic groups
284. 15.7.4: Nicholas Wareham: Prevention of Type 2 Diabetes
285. 15.8: Emerging Approaches to Restoring Euglycaemia in Diabetes
286. 15.8.1: Michael White, Timothy J. Kieffer, and Cara Ellis: Regenerative
medicine for diabetes
287. 15.8.2: Roman Hovorka and Charlotte Boughton: Closed loop
288. 15.9: Emergency and Hospital management of Diabetes
289. 15.9.1: Ketan Dhatariya: Hyperglycaemic Emergencies
290. 15.9.2: Gerry Rayman: Management of the inpatient with diabetes mellitus
291. 15.9.3: Greet Van Den Berghe and Jan Gunst: Care of diabetes in ICU and
peri-sugery
292. 15.10: Specialised Management of Other forms of Diabetes
293. 15.10.1: Andrew Hattersley, Kashyap Patel, and Rachel Besser: Monogenic
forms of diabetes resulting from beta cell dysfunction
294. 15.10.2: Anna Stears, David B. Savage, and Stephen O'Rahilly:
Lipodystrophies and severe insulin resistance
295. 15.10.3.1: Phil Weston: Diabetes Secondary to Pancreatic Disease
296. 15.10.3.2: Jeremy Tomlinson: Diabetes Secondary to Endocrine Disorders
297. 15.10.4: Helen Murphy and Jennifer M Yamamoto: Diabetes in Pregnancy
298. 15.11: Psychiatry and Diabetes
299. 15.11.1: Khalida Ismail, Christopher Garrett, and Marietta Stadler: Type 1
diabetes and Psychiatry
300. 15.11.2: Khalida Ismail, Hermione Price, Marilia Calcia, Calum Moulton, and
Clare Whicher: Type 2 diabetes and Psychiatry
301. 15.12: Microvascular Complications of Diabetes
302. 15.12.1: Angela Shore: Pathogenesis of Microvascular Complications
303. 15.12.2: Peter Scanlon: Retinopathy
304. 15.12.3: Luigi Gnudi and Sally Marshall: Diabetic Nephropathy
305. 15.12.4: Solomon Tesfaye and Jing Wu: Diabetic Neuropathy
306. 15.13: Macrovascular Disease in Diabetes
307. 15.13.1: Mark Kearney, Peysh Patel, and Richard Cubbon: Mechanisms of
macrovascular disease in diabetes
308. 15.13.2: Naveed Sattar: Macrovascular disease in type 2 diabetes
309. 15.13.3: John Petrie: Macrovascular disease in type 1 diabetes
310. 15.13.4: Bruno Vergès: Diabetic dyslipidaemia
311. 15.13.5: Bryan Williams: Hypertension in diabetes melli
2. 1.1: Lynn Loriaux: Endocrine Practice Fundamentals
3. 1.2: John W. Funder: Hormones and receptors: fundamental considerations
4. 1.3: Ken Siddle and Gemma Brierley: Molecular aspects of hormonal
regulation
5. 1.4: Janine A. Danks and Samantha J. Richardson: Endocrinology and
evolution: lessons from comparative endocrinology
6. 1.5: James Gibney, Indi Banerjee, and Ken Ho: Hormones Across the Lifespan
7. 1.6: Brian Keevil, Peter Trainer, and William Drake: Pituitary assessment
strategy
8. 1.7: Simon Pearce and Catherine Owen: Endocrine autoimmunity
9. 1.8: Jerome Bertherat, Anne Jouinot, and Fidéline Bonnet-Serrano: Common
Features of Endocrine Tumours
10. 1.9: Trevor Cole: Genetic Aspects of Endocrine Disease
11. 1.10: George Mastorakos, Markella Nezi, Djuro Macut, and Maria Papagianni:
Environmental Influences on Endocrine Disease
12. 1.11: Georg Brabant and H. Oster: Endocrinology, sleep and circadian
rhythms
13. 1.12: Richard Ross: Principles of Hormone replacement
14. 1.13: Jonathan Valabhji and Rochan Agha-Jaffar: Prevention in endocrinology
15. 2. Pituitary and hypothalamic diseases
16. 2.1: John Morris: Functional anatomy of the hypothalamus and pituitary
17. 2.2: Stephen G. Ball: The neurohypophysis
18. 2.3: Aetiology, pathogenesis, and management of disease of the pituitary
19. 2.3.1: Mehul T. Dattani and Louise C. Gregory: Development of the pituitary
and genetic forms of hypopituitarism
20. 2.3.2: Shlomo Melmed: Molecular pathogenesis of pituitary tumours
21. 2.3.3: Luis Syro, Kalman Kovacs, and Fabio Rotondo: Histopathology of
pituitary tumours
22. 2.3.4: Jean-Francois Bonneville, Sonia Nagi, and Iulia Potorac: Imaging of
the pituitary
23. 2.3.5: Miles J. Levy, Ragini Bhake, and Narendra Reddy: Hypopituitarism:
replacement of adrenal, thyroid, and gonadal axes
24. 2.3.6: Jens Jørgensen: Adult growth hormone deficiency
25. 2.3.7: Edward R. Laws Jr, David L. Penn, and Caroline S. Repetti: Surgery
of pituitary tumours
26. 2.3.8: Naomi Fersht and Francesca Solda: Pituitary radiotherapy
27. 2.3.9: Nicholas Tritos and Anne Klibanski: Prolactinomas and
hyperprolactinaemia (including macroprolactinaemia)
28. 2.3.10: John Wass, Peter J. Trainer, and Márta Korbonits: Acromegaly
29. 2.3.11: Nienke Biermasz and Wouter R. van Furth: Clinically nonfunctioning
pituitary tumours and gonadotropinomas
30. 2.3.12: Mark Gurnell, Olympia Koulouri, and Waiel Bashari: Thyrotropinomas
31. 2.3.13: Ann McCormack: Pituitary carcinoma
32. 2.3.14: Niki Karavitaki, Shu Teng Chai, and Shahzada Ahmed: Pituitary
incidentalomas
33. 2.4: Aetiology, pathogenesis, and management of diseases of the
hypothalamus
34. 2.4.1: Mehul Dattani, Hoong-Wei Gan, and Manuela Cerbone: Hypothalamic
dysfunction (hypothalamic syndromes)
35. 2.4.2: Niki Karavitaki: Craniopharyngiomas
36. 2.4.3: Jürgen Honegger, Ulrike Ernemann, and Rudi Beschorner: Perisellar
tumours including cysts, hamartomas, and vascular tumours
37. 2.4.4: Mark E. Molitch and Jelena Kravarusic: Lymphocytic hypophysitis and
other inflammatory conditions of the pituitary
38. 2.5: Susan M Webb, Anna Aulinas, Cristina Colom, and José Barahona: Pineal
physiology and pathophysiology, including pineal tumours
39. 3. The Thyroid
40. 3.1: Evaluation of the thyroid patient
41. 3.1.1: Robert Volpé and Clark Sawin: The history and iconography relating
to the thyroid gland
42. 3.1.2: W. Edward Visser: Biosynthesis, transport, metabolism, and actions
of thyroid hormones
43. 3.1.3: Inge Bülow Pedersen and Stig Andersen: Clinical assessment of the
thyroid patient
44. 3.1.4: Ulla Feldt-Rasmussen: Thyroid function tests and the effects of
drugs
45. 3.1.5: Robin P. Peeters and Anita Boelen: Nonthyroidal illness syndrome
46. 3.1.6: Steen Bonnema and Laszlo Hegedüs: Thyroid imaging: nuclear medicine
techniques
47. 3.1.7: Laszlo Hegedüs and Finn N. Bennedbæk: Thyroid imaging: nonisotopic
techniques
48. 3.1.8: Mark P. J. Vanderpump: Epidemiology of thyroid disease and swelling
49. 3.2: Aetiology of thyroid disorders
50. 3.2.1: Terry Davies, Francesca Menconi, and Yaron Tomer: The complex
genetics of thyroid disease
51. 3.2.2: Josef Köhrle: Environmental factors
52. 3.2.3: Michael B. Zimmermann: Iodine deficiency disorders
53. 3.2.4: Shunichi Yamashita, Furio Pacini, and Rossella Elisei:
Radiation-induced thyroid disease
54. 3.2.5: Anthony P. Weetman: Autoimmune thyroid disease
55. 3.2.6: Elizabeth N. Pearce and Alan Farwell: Thyroiditis
56. 3.3: Thyrotoxicosis and related disorders
57. 3.3.1: Claudio Marcocci and Filomena Cetani: Clinical assessment and
systemic manifestations of thyrotoxicosis
58. 3.3.2: Annie W. C. Kung and C.L. Cheung: Thyrotoxic periodic paralysis
59. 3.3.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Thyrotoxic storm
60. 3.3.4: Simon Pearce: Subclinical hyperthyroidism
61. 3.3.5: Francesco Latrofa and Paolo Vitti: Causes and laboratory
investigations of thyrotoxicosis
62. 3.3.6: Luigi Bartalena: Anti-thyroid drug treatment for thyrotoxicosis
63. 3.3.7: Markus Luster and Michael Lassmann: Radio-iodine treatment of
hyperthyroidism
64. 3.3.8: Nancy Dugal Perrier, Orlo Clark, and Sarah B. Fisher: Surgery for
thyrotoxicosis
65. 3.3.9: Jacques Orgiazzi: Management of Graves hyperthyroidism
66. 3.3.10: Wilmar M. Wiersinga: Graves orbitopathy and dermopathy
67. 3.3.11: Dagmar Führer and Holger Jäschke: Management of toxic multinodular
goitre and toxic adenoma
68. 3.3.12: Wilmar M. Wiersinga: Management of thyrotoxicosis without
hyperthyroidism
69. 3.4: Hypothyroidism
70. 3.4.1: Massimo Tonacchera and Luca Chiovato: Clinical assessment and
systemic manifestations of hypothyroidism
71. 3.4.2: Ferruccio Santini: Causes and laboratory investigation of
hypothyroidism
72. 3.4.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Myxoedema coma
73. 3.4.4: Bijay Vaidya and Chantal Daumerie: Subclinical hypothyroidism
74. 3.4.5: Mark Gurnell, Carla Moran, and V. K. Chatterjee: Syndromes of
Resistance to Thyroid Hormone
75. 3.4.6: Birte Nygaard: Treatment of hypothyroidism
76. 3.5: Thyroid lumps
77. 3.5.1: Dagmar Führer and Holger Jäschke: Pathogenesis of nontoxic goitre
78. 3.5.2: Hans Graf and Gilberto Paz Filho: Management of nontoxic
multinodular goitre
79. 3.5.3: Laszlo Hegedüs and Finn N. Bennedbæk: Management of the single
thyroid nodule
80. 3.5.4: Massimo Santoro, Barbara Jarzab, Jolanta Krajewska, and Dagmara
Rusinek: Pathogenesis of thyroid cancer
81. 3.5.5: Fulvio Basolo and Clara Ugolini: Pathology of thyroid cancer
82. 3.5.6: Corin Badiu and Ruxandra Dobrescu: Papillary, follicular, and
anaplastic thyroid carcinoma and lymphoma
83. 3.5.7: Friedhelm Raue and Karin Frank-Raue: Medullary thyroid carcinoma
84. 4. Parathyroid, calcium, and bone metabolism
85. 4.1: David Goltzman and Geoffrey N. Hendy: Parathyroid anatomy, hormone
synthesis, secretion, action, and receptors
86. 4.2: Claudio Marcocci, Federica Saponaro, and Filomena Cetani:
Hypercalcaemia
87. 4.3: John P. Bilezikian: Primary hyperparathyroidism
88. 4.4: Dolores Shoback and Muriel Babey: Familial Hypocalciuric Hypercalcemia
Types 1-3 and Neonatal Severe Primary Hyperparathyroidism
89. 4.5: Rajesh Thakker, Bart Clarke, and Fadil M. Hannan: Hypocalcaemic
disorders, hypoparathyroidism, and pseudohypoparathyroidism
90. 4.6: Paul D. Miller and Michael Pazianas: Bones and the Kidney-The
Practical Conundrum: Distinguishing Between Osteoporosis and the Bone
Diseases that Accompany Chronic Renal Failure
91. 4.7: Laleh Ardeshirpour, Thomas O. Carpenter, and Cemre Robinson:
Hypercalcaemic and hypocalcaemic syndromes in children
92. 4.8: Richard Eastell: Osteoporosis
93. 4.9: Graham R. Williams, J. H. Duncan Bassett, Bernard Freudenthal, and
Laura M. Watts: Thyroid disorders and bone disease
94. 4.10: Socrates E. Papapoulos: Paget s disease of bone
95. 4.11: Michael P. Whyte: Rickets and osteomalacia (acquired and heritable
forms)
96. 4.12: Gherardo Mazziotti, Ernesto Canalis, and John P. Bilezikian:
Glucocorticoid-induced osteoporosis
97. 5. The adrenal gland and endocrine hypertension
98. 5.1: Peter Guest: Adrenal imaging
99. 5.2: Fausto Palazzo and Radu Mihai: Adrenal surgery
100. 5.3: Irina Bancos, Massimo Terzolo, and Wiebke Arlt: Adrenal incidentaloma
101. 5.4: Jérôme Bertherat, Rossella Libè, and Anne Jouinot: Adrenocortical
cancer
102. 5.5.1: Eamonn R. Maher and Ruth T Casey: Genetics of phaeochromocytomas,
paragangliomas, and neuroblastoma
103. 5.5.2: Henri Timmers: Management of phaeochromocytoma and paragagnlioma
104. 5.6.1: Maria Christina Zennaro, Fabio Fernandes-Rosa, and Sheerazed
Boulkroun: Genetics of primary aldosteronism and other steroid-related
causes of endocrine hypertension
105. 5.6.2: Morris Brown and Will Drake: Management of primary aldosteronism
106. 5.7: John Newell-Price: Cushing s syndrome
107. 5.8.1: Li Chan and Shwetha Ramachandrappa: Genetics of Adrenal
Insufficiency
108. 5.8.2: Wiebke Arlt: Management of Adrenal Insufficiency
109. 5.9.1: Nils P. Krone: Genetics of congenital adrenal hyperplasia
110. 5.9.2: Richard J. Auchus: Modern management of congenital adrenal
hyperplasia and prospects for the future
111. 6. Neuroendocrine tumours and genetic disorders
112. 6.1: Guido Rindi and Rajaventhan Srirajaskanthan: Overview and
Pathophysiology of Neuroendocrine Neoplasms
113. 6.2: Whaljit Dhillo and Paul Bech: Neuroendocrine tumour markers
114. 6.3: Rajaventhan Srirajaskanthan, Martyn E. Caplin, and Dominique Clement:
Carcinoid syndrome
115. 6.4.1: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor: Lung
neuroendocrine tumours
116. 6.4.2: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor:
Non-functioning pancreatic neuroendocrine tumours
117. 6.5: Christos Toumpanakis and Martyn E. Caplin: Gastrinoma
118. 6.6: Ashley Grossman and Ingrid YF Mak: Insulinoma and hypoglycaemia
119. 6.7: Karim Meeran: Glucagonoma
120. 6.8: Alia Munir: Vasointestinal Polypeptide Secreting Tumours
121. 6.9: John Wass: Somatostatinoma
122. 6.10: Prakash Manoharan: Imaging neuroendocrine tumours of the
gastrointestinal tract/gastroenteropancreatic neuroendocrine tumours
(GEP-NET)
123. 6.11: Rajesh V. Thakker: Multiple endocrine neoplasia type 1
124. 6.12: Electron Kebebew, Douglas Wiseman, and Mustapha El Lakis: Multiple
endocrine neoplasia type 2a and 2b
125. 6.13: Eamonn R. Maher and Ruth T. Casey: Familial syndromes and genetic
causes of paraganglioma and phaeochromocytoma
126. 6.14: Constantine A. Stratakis and Fabio Faucz: Carney s complex
127. 6.15: Michael A. Levine and Steven A. Lietman: Molecular and Clinical
Characteristics Of the McCune-Albright Syndrome
128. 6.16: Charis Eng, Lamis Yehia, and Shreya Malhotra: Cowden syndrome
129. 7. Growth and development during childhood and adolescence
130. 7.1: Growth and its Disorders
131. 7.1.1: Gary Butler: Recognising Normal and Disordered Growth
132. 7.1.2: Alexander A. L. Jorge, Fernanda A. Correa, and Renata C. Scalco:
Disorders of the GH-IGF Axis
133. 7.1.3: Anita Hokken-Koelega: Short stature in children born small for
gestational age
134. 7.1.4: Steve Chernausek and Minu George: Growth Disorders with no defined
aetiology
135. 7.1.5: Lars Savendahl and Emelie Benji: Tall Stature
136. 7.2: Sex Development
137. 7.2.1: Olaf Hiort and Ralf Werner: Sex Determination and Differentiation
138. 7.2.2: S. Faisal Ahmed and Salma R. Ali: Disorders of Sex Development (DSD)
in the newborn
139. 7.2.3: Alan Rogol and John Fuqua: Recognising Normal and Disordered
Pubertal Development
140. 7.2.4: Alan Rogol and John Fuqua: Pubertal Delay and Hypogonadism
141. 7.2.5: Julianne Leger and Jean-Claude Carel: Precocious Puberty
142. 7.3: Helena Gleeson and Rohana Wright: Transition In Endocrinology
143. 8. Female endocrinology and pregnancy
144. 8.1: Normal female endocrinology and ovarian disorders
145. 8.1.1: Chris McCartney and John Marshall: Neuroendocrinology of
reproduction: the role of hypothalamus and pituitary
146. 8.1.2: Terhi Piltonen and Juha Tapanainen: Ovarian and uterine development
from fetal life to puberty
147. 8.1.3: Gurkan Bozdag, Baris Ata, and Engin Türkgeldi: Menstrual cycle and
ovulation
148. 8.2: Evaluation of the female patient with suspected reproductive endocrine
disorders
149. 8.2.1: Channa Jayasena, Steve Franks, and Rachel Roberts: Clinical
evaluation of patient with suspected reproductive endocrine disorders
150. 8.2.2: Daniel Dumesic and Zain Al-Safi: Laboratory evaluation
151. 8.3: Reproductive endocrine disorders
152. 8.3.1: Sarah L. Berga: Disorders of gonadotrophin secreton
153. 8.3.2: Julian R. E. Davis and Agnieszka Swiecicka: Hyperprolactinaemia
154. 8.3.3: Deepthi Lavu, Radha Indusekhar, and Shaughn O'Brien: Premenstrual
syndrome
155. 8.4: Polycystic ovary syndrome and other androgen excess disorders
156. 8.4.1: Bulent Yildiz and Sezcan Mumusoglu: Polycystic ovary syndrome:
definitions, phenotypes, prevalence and genetics
157. 8.4.2: R Jeffrey Chang: Polycystic ovary syndrome: reproductive aspects
158. 8.4.3: David Ehrmann and Susan Sam: Polycystic ovary syndrome: metabolic
aspects
159. 8.4.4: Duarte Pignatelli, Ricardo Azziz, and Bulent Yildiz: Polycystic
ovary syndrome: Hirsutism
160. 8.5: Female hypogonadism and menopause
161. 8.5.1: Ephia Yasmin and Gerard S. Conway: Female hypogonadism: premature
ovarian insufficiency
162. 8.5.2: Dimitrios G. Goulis, Stavroula A. Paschou, and Panagiotis
Anagnostis: Female hypogonadism: Endocrinology of the menopause and hormone
replacement therapy
163. 8.6: Female infertility
164. 8.6.1: Adam Balen and Susie Jacob: Female Infertility and assisted
reproduction
165. 8.6.2: Kutluk Oktay and Enes Taylan: Female infertility: fertility
preservation
166. 8.7: Hormonal contraception
167. 8.7.1: Jennifer Chin Bliss Kaneshiro: Hormonal contraception
168. 8.8: Exogenous factors and female repoductive health
169. 8.8.1: Alessandra Gambineri and Daniela Ibarra-Gasparini: Exogenous factors
and female reproductive health: common extragonadal endocrinopathies
affecting reproduction
170. 8.8.2: Siew Lim, Aya Mousa, Soulmaz Shorakae, and Lisa Moran: Exogenous
factors and female reproductive health: nutrition and reproduction
171. 8.8.3: Evy Diamanti-Kandarakis and Eleni A Kandaraki: Exogenous factors and
female reproductive health: envrionment and reproduction
172. 9. Endocrinology of pregnancy
173. 9.1: Endocrine disorders of Pregnancy
174. 9.1.1: Peter Taylor, LDKE Premawardhana, and John Lazarus: General
considerations relating to thyroid disease in pregnancy
175. 9.1.2: Kris Poppe, Flora Veltri, and David Unuane: Management of thyroid
disorders before assisted and spontaneous pregnancy
176. 9.1.3: Tim Korevaar and Robin Peeters: Thyroid disease during pregnancy
177. 9.1.4: Nobuyuki Amino and Naoko Arata: Management of thyroid disorders
after pregnancy
178. 9.1.5: A. S. Paul van Trotsenburg Nitash and Zwaveling-Soonawala: Thyroid
disorders in newborns, infants and children
179. 9.1.6: Mark Molitch and Wenyu Huang: Pituitary tumours in pregnancy
180. 9.1.7: Paul Carroll, Niki Karavitaki, and Kirstie Lithgow: Other disorders
of the pituitary and hypothalamus in pregnancy
181. 9.1.8: David Torpy, Michael O'Reilly, and Sunita De Sousa: Adrenal disease
in pregnancy
182. 9.1.9: Jeremy Cox and Stephen Robinson: Endocrine bone disease in pregnancy
183. 9.1.10: Sandra Lowe: Imaging of endocrine disorders in pregnancy
184. 10. Male Reproductive Endocrinology
185. 10.1: Normal male reproductive endocrinology
186. 10.1.1: Ilpo Huhtaniemi and Jorma Toppari: Endocrine and local regulation
of testicular hormone and sperm production
187. 10.1.2: Dirk Vanderschueren, Leen Antonio, Nari Kim, and Frank Claessens:
Sex steroid actions in the Male
188. 10.2: Evaluation of the male patient with suspected hypogonadism and/or
infertility
189. 10.2.1: Bradley Anawalt: Clinical evaluation
190. 10.2.2: Jean-Marc Kaufman: Endocrine evaluation
191. 10.2.3: Jackson Kirkman-Brown and Sarah J Conner: Diagnostic Semen analysis
192. 10.3: Male reproductive endocrine disorders
193. 10.3.1: Claus H. Gravholt: Klinefelter s syndrome
194. 10.3.2: Adult Hypogonadism: Aetiology
195. 10.3.2.1: Alvin Matsumoto and Radhika Narla: Etiology of Hypogonadism
196. 10.3.2.2: Giovanni Corona, Mario Maggi, and Giulia Rastrelli: Types of
Treatments
197. 10.3.2.3: Michael Zitzmann: Gonadotrophin induction of spermatogenesis
198. 10.3.2.4: Shehzad Basaria and Thiago Gagliano-Juca: Male Hypogonadism:
Benefits of Testosterone Treatment
199. 10.3.2.5: Adrian Dobs and Swaytha Yalamanchi: Risks of T Treatment
200. 10.3.3: Herman J. Tournaye and Biljana Popovic-Todorovic: Management of
Idiopathic male infertility
201. 10.3.4: Mathis Grossmann, B. Yeap, and Gary Wittert:
Hypothalamo-pituitary-testicular axis fucntion in systemic diseases and
effects of medications
202. 10.3.5: Vincenzo Rochira, Antonio R. M. Granata, and Cesare Carani:
Management of sexual dysfunction
203. 10.3.6: Stephanie Page and Maritza Farrant: Hormonal male contraception
204. 10.3.7: Glenn Braunstein: Gynaecomastia
205. 10.4: Exogenous factors and male reproductive health
206. 10.4.1: Jorma Toppari: Environmental influences on male reproductive health
207. 10.4.2: David Handelsman: Androgen Misuse and Abuse
208. 11. Management of the Transgender Patient
209. 11.1: Jon Arcelus and Walter Bouman: Introduction to Transgender and Gender
Diverse People
210. 11.2: Daniel Klink: Endocrine Treatment of Transgender Youth
211. 11.3: Vin Tangpricha and Craig Sineath: Hormone Therapy in transgender
women
212. 11.4: Guy T'Sjoen and Justine Defreyne: Hormone therapy in transgender men
213. 11.5: Chloë De Roo and Guy T'Sjoen: Fertility Options for Transgender
Persons
214. 12. Endocrine Responses to Systemic Diseases or Substance Use
215. 12.1: Endocrinology of systemic disease
216. 12.1.1: David Henley, Thomas Upton, and Stafford L. Lightman: The endocrine
response to stress
217. 12.1.2: Greet Van den Berghe and Lies Langouche: Endocrinology in the
critically ill
218. 12.1.3: David Johnson, Melissa Nataatmadja, and Yeoungjee Cho: Hormones and
the kidney
219. 12.1.4: Jacob George and Mohammed Eslam: The endocrinology of liver disease
220. 12.1.5: Steven K. Grinspoon and Takara Stanley: Endocrine abnormalities in
HIV infection
221. 12.1.6: Karen Miller: The endocrinology of anorexia nervosa
222. 12.2: Endocrine Complications of Substance Misuse
223. 12.2.1: Marc Walter and Margit Proescholdt: Endocrinology and alcohol
224. 12.2.2: Peter Sonksen and Richard Holt: Use and abuse of
performance-enhancing hormones in sport
225. 12.2.3: Ashley Grossman, Eleni Armeni, and Bernard Khoo: Effect of Opioids
on Adrenal and Reproductive Endocrinology
226. 13. Endocrinology of cancer
227. 13.1: Endocrine Disorders Caused by Cancer or its Treatment
228. 13.1.1: Thomas Papathomas and Vania Nose: Metastatic Disease in Endocrine
Organs
229. 13.1.2: David W. Ray: Paraneoplastic endocrine syndromes
230. 13.1.3: Claire Higham and Rob Murray: Long-term endocrine sequelae of
cancer therapy
231. 13.1.4: Carla Moran: Endocrine complications of biological cancer therapies
232. 13.2: Hormonal therapy for breast and prostatic cancers
233. 13.2.1: Rob Clarke and Alice Greenhalgh: The breast: lactation and breast
cancer as an endocrine disease
234. 13.2.2: Amna Sheri and Laura Morrison: Endocrine treatment of breast cancer
235. 13.2.3: Irina A. Vasilevskaya, Matthew J. Schiewer, and Karen E. Knudsen:
Hormonal Therapy for Prostate Cancer: Molecular basis of efficacy and
therapeutic bypass
236. 14. Obesity, lipids, and metabolic disorders
237. 14.1: Obesity
238. 14.1.1: Anthony Coll: The Physiology of Bodyweight Regulation
239. 14.1.2: Adrian Bauman: Obesity as a Public Health Problem
240. 14.1.3: Rachel Batterham and Friedrich Jassil: Medical Complications of
Obesity
241. 14.1.4: John Wilding and Jonathan Lim: Dietary and Medical Management of
Obesity
242. 14.1.5: Francesco Rubino, Vivian Anastasiou, Luca Ferraro, Dalal Qanaq, and
Ghassan Chamseddine: Metabolic Surgery
243. 14.1.6: Sadaf Farooqi: Assessment of Obesity in Children
244. 14.1.7: Russell Viner and Billy White: Management of Obesity in Children
and Young People
245. 14.1.8: Nick Finer: Planning obesity care pathways
246. 14.2: Lipoprotein metabolism and dyslipidaemia
247. 14.2.1: Bo Angelin and Paolo Parini: Lipoprotein metabolism
248. 14.2.2: Stefano Romeo, Bo Angelin, and Paolo Parini: Genetic forms of
dyslipidaemia
249. 14.3: Other metabolic disorders
250. 14.3.1: Khalid Hussain and Sonya Galcheva: Hyperinsulinaemic Hypoglycaemia
251. 14.3.2: Phillip Gorden and Noemi Malandrino: Autoimmune Hypoglycaemia
252. 14.3.3: Robin H. Lachmann: Disorders of carbohydrate metabolism
253. 14.3.4: Yves Deugnier and Edouard Bardou-Jacquet: Haemochromatosis And
Other Inherited Diseases Of Iron Metabolism
254. 14.3.5: Michael N. Badminton and Danja Schulenburg-Brand: The porphyrias
255. 15. Diabetes mellitus
256. 15.1: Introduction to Diabetes Mellitus
257. 15.1.1: Shanta Persaud and Peter Jones: Physiology of glucose homeostasis
258. 15.1.2: Stephen Colagiuri and Crystal Man Ying Lee: Classification and
diagnosis of diabetes mellitus
259. 15.2: Aetiopathogenesis and Diagnosis of Type 1 Diabetes
260. 15.2.1: Elizabeth J. Mayer-Davis and Daria Igudesman: Epidemiology and
Public Health
261. 15.2.2: Augustin Brooks: Presentation and Natural History
262. 15.2.3: Richard Oram, Susan Wong, and Ayat Bashir: Pathogenesis
263. 15.3: Aetiopathogenesis and Diagnosis of Type 2 Diabetes
264. 15.3.1: Sarah Wild and Jackie Price: Epidemiology and Public Health
265. 15.3.2: Roy Taylor: Presentation and Natural History
266. 15.3.3: Mark Walker, Xuefei Yu, and Amalia Gastaldelli: Pathogenesis
267. 15.4: Non Type 1, Non Type 2 Diabetes
268. 15.4.1: Katherine Owen: Diagnosis of non type 1, non type 2 forms of
diabetes
269. 15.5: Principles of Management of Diabetes
270. 15.5.1: Simon Heller and Jackie Elliott: Structured Education
271. 15.5.2: John Pickup and Nick Oliver: Glucose Monitoring and Sensing
272. 15.5.3: Pratik Choudhary and Peter Jacob: Insulins and insulin delivery
devices
273. 15.5.4: Clifford Bailey and Melanie Davies: Non-insulin glucose lowering
agents
274. 15.5.5: Stephanie Amiel: Hypoglycaemia in the treatment of diabetes
mellitus
275. 15.6: Evidence-based Management of Type 1 Diabetes
276. 15.6.1: Peter Hammond and Fiona Campbell: Strategies for management of type
1 diabetes
277. 15.6.2: Christel Hendrieckx and Jane Speight: Psychological and Behavioural
Aspects of Type 1 Diabetes Management
278. 15.6.3: Colin Dayan and Danijela Tatovic: Immunotherapy for type 1 diabetes
279. 15.6.4: Peter Senior, Martin Drage, Anneliese Flatt, and Chris Callaghan:
Transplantation (islet and solid organ)
280. 15.7: Evidence-based Prevention and Management of Type 2 Diabetes
281. 15.7.1: Peter Winocour and Sagen Zac-Varghese: Strategies for management of
type 2 diabetes
282. 15.7.2: Jane Speight and Tim Skinner: Psychological and Behavioural Aspects
of Type 2 Diabetes Management
283. 15.7.3: Kamiesh Khunti and Nitin Narayan Gholap: Type 2 diabetes in
different ethnic groups
284. 15.7.4: Nicholas Wareham: Prevention of Type 2 Diabetes
285. 15.8: Emerging Approaches to Restoring Euglycaemia in Diabetes
286. 15.8.1: Michael White, Timothy J. Kieffer, and Cara Ellis: Regenerative
medicine for diabetes
287. 15.8.2: Roman Hovorka and Charlotte Boughton: Closed loop
288. 15.9: Emergency and Hospital management of Diabetes
289. 15.9.1: Ketan Dhatariya: Hyperglycaemic Emergencies
290. 15.9.2: Gerry Rayman: Management of the inpatient with diabetes mellitus
291. 15.9.3: Greet Van Den Berghe and Jan Gunst: Care of diabetes in ICU and
peri-sugery
292. 15.10: Specialised Management of Other forms of Diabetes
293. 15.10.1: Andrew Hattersley, Kashyap Patel, and Rachel Besser: Monogenic
forms of diabetes resulting from beta cell dysfunction
294. 15.10.2: Anna Stears, David B. Savage, and Stephen O'Rahilly:
Lipodystrophies and severe insulin resistance
295. 15.10.3.1: Phil Weston: Diabetes Secondary to Pancreatic Disease
296. 15.10.3.2: Jeremy Tomlinson: Diabetes Secondary to Endocrine Disorders
297. 15.10.4: Helen Murphy and Jennifer M Yamamoto: Diabetes in Pregnancy
298. 15.11: Psychiatry and Diabetes
299. 15.11.1: Khalida Ismail, Christopher Garrett, and Marietta Stadler: Type 1
diabetes and Psychiatry
300. 15.11.2: Khalida Ismail, Hermione Price, Marilia Calcia, Calum Moulton, and
Clare Whicher: Type 2 diabetes and Psychiatry
301. 15.12: Microvascular Complications of Diabetes
302. 15.12.1: Angela Shore: Pathogenesis of Microvascular Complications
303. 15.12.2: Peter Scanlon: Retinopathy
304. 15.12.3: Luigi Gnudi and Sally Marshall: Diabetic Nephropathy
305. 15.12.4: Solomon Tesfaye and Jing Wu: Diabetic Neuropathy
306. 15.13: Macrovascular Disease in Diabetes
307. 15.13.1: Mark Kearney, Peysh Patel, and Richard Cubbon: Mechanisms of
macrovascular disease in diabetes
308. 15.13.2: Naveed Sattar: Macrovascular disease in type 2 diabetes
309. 15.13.3: John Petrie: Macrovascular disease in type 1 diabetes
310. 15.13.4: Bruno Vergès: Diabetic dyslipidaemia
311. 15.13.5: Bryan Williams: Hypertension in diabetes melli
1. 1. Principles of basic and clinical endocrinology
2. 1.1: Lynn Loriaux: Endocrine Practice Fundamentals
3. 1.2: John W. Funder: Hormones and receptors: fundamental considerations
4. 1.3: Ken Siddle and Gemma Brierley: Molecular aspects of hormonal
regulation
5. 1.4: Janine A. Danks and Samantha J. Richardson: Endocrinology and
evolution: lessons from comparative endocrinology
6. 1.5: James Gibney, Indi Banerjee, and Ken Ho: Hormones Across the Lifespan
7. 1.6: Brian Keevil, Peter Trainer, and William Drake: Pituitary assessment
strategy
8. 1.7: Simon Pearce and Catherine Owen: Endocrine autoimmunity
9. 1.8: Jerome Bertherat, Anne Jouinot, and Fidéline Bonnet-Serrano: Common
Features of Endocrine Tumours
10. 1.9: Trevor Cole: Genetic Aspects of Endocrine Disease
11. 1.10: George Mastorakos, Markella Nezi, Djuro Macut, and Maria Papagianni:
Environmental Influences on Endocrine Disease
12. 1.11: Georg Brabant and H. Oster: Endocrinology, sleep and circadian
rhythms
13. 1.12: Richard Ross: Principles of Hormone replacement
14. 1.13: Jonathan Valabhji and Rochan Agha-Jaffar: Prevention in endocrinology
15. 2. Pituitary and hypothalamic diseases
16. 2.1: John Morris: Functional anatomy of the hypothalamus and pituitary
17. 2.2: Stephen G. Ball: The neurohypophysis
18. 2.3: Aetiology, pathogenesis, and management of disease of the pituitary
19. 2.3.1: Mehul T. Dattani and Louise C. Gregory: Development of the pituitary
and genetic forms of hypopituitarism
20. 2.3.2: Shlomo Melmed: Molecular pathogenesis of pituitary tumours
21. 2.3.3: Luis Syro, Kalman Kovacs, and Fabio Rotondo: Histopathology of
pituitary tumours
22. 2.3.4: Jean-Francois Bonneville, Sonia Nagi, and Iulia Potorac: Imaging of
the pituitary
23. 2.3.5: Miles J. Levy, Ragini Bhake, and Narendra Reddy: Hypopituitarism:
replacement of adrenal, thyroid, and gonadal axes
24. 2.3.6: Jens Jørgensen: Adult growth hormone deficiency
25. 2.3.7: Edward R. Laws Jr, David L. Penn, and Caroline S. Repetti: Surgery
of pituitary tumours
26. 2.3.8: Naomi Fersht and Francesca Solda: Pituitary radiotherapy
27. 2.3.9: Nicholas Tritos and Anne Klibanski: Prolactinomas and
hyperprolactinaemia (including macroprolactinaemia)
28. 2.3.10: John Wass, Peter J. Trainer, and Márta Korbonits: Acromegaly
29. 2.3.11: Nienke Biermasz and Wouter R. van Furth: Clinically nonfunctioning
pituitary tumours and gonadotropinomas
30. 2.3.12: Mark Gurnell, Olympia Koulouri, and Waiel Bashari: Thyrotropinomas
31. 2.3.13: Ann McCormack: Pituitary carcinoma
32. 2.3.14: Niki Karavitaki, Shu Teng Chai, and Shahzada Ahmed: Pituitary
incidentalomas
33. 2.4: Aetiology, pathogenesis, and management of diseases of the
hypothalamus
34. 2.4.1: Mehul Dattani, Hoong-Wei Gan, and Manuela Cerbone: Hypothalamic
dysfunction (hypothalamic syndromes)
35. 2.4.2: Niki Karavitaki: Craniopharyngiomas
36. 2.4.3: Jürgen Honegger, Ulrike Ernemann, and Rudi Beschorner: Perisellar
tumours including cysts, hamartomas, and vascular tumours
37. 2.4.4: Mark E. Molitch and Jelena Kravarusic: Lymphocytic hypophysitis and
other inflammatory conditions of the pituitary
38. 2.5: Susan M Webb, Anna Aulinas, Cristina Colom, and José Barahona: Pineal
physiology and pathophysiology, including pineal tumours
39. 3. The Thyroid
40. 3.1: Evaluation of the thyroid patient
41. 3.1.1: Robert Volpé and Clark Sawin: The history and iconography relating
to the thyroid gland
42. 3.1.2: W. Edward Visser: Biosynthesis, transport, metabolism, and actions
of thyroid hormones
43. 3.1.3: Inge Bülow Pedersen and Stig Andersen: Clinical assessment of the
thyroid patient
44. 3.1.4: Ulla Feldt-Rasmussen: Thyroid function tests and the effects of
drugs
45. 3.1.5: Robin P. Peeters and Anita Boelen: Nonthyroidal illness syndrome
46. 3.1.6: Steen Bonnema and Laszlo Hegedüs: Thyroid imaging: nuclear medicine
techniques
47. 3.1.7: Laszlo Hegedüs and Finn N. Bennedbæk: Thyroid imaging: nonisotopic
techniques
48. 3.1.8: Mark P. J. Vanderpump: Epidemiology of thyroid disease and swelling
49. 3.2: Aetiology of thyroid disorders
50. 3.2.1: Terry Davies, Francesca Menconi, and Yaron Tomer: The complex
genetics of thyroid disease
51. 3.2.2: Josef Köhrle: Environmental factors
52. 3.2.3: Michael B. Zimmermann: Iodine deficiency disorders
53. 3.2.4: Shunichi Yamashita, Furio Pacini, and Rossella Elisei:
Radiation-induced thyroid disease
54. 3.2.5: Anthony P. Weetman: Autoimmune thyroid disease
55. 3.2.6: Elizabeth N. Pearce and Alan Farwell: Thyroiditis
56. 3.3: Thyrotoxicosis and related disorders
57. 3.3.1: Claudio Marcocci and Filomena Cetani: Clinical assessment and
systemic manifestations of thyrotoxicosis
58. 3.3.2: Annie W. C. Kung and C.L. Cheung: Thyrotoxic periodic paralysis
59. 3.3.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Thyrotoxic storm
60. 3.3.4: Simon Pearce: Subclinical hyperthyroidism
61. 3.3.5: Francesco Latrofa and Paolo Vitti: Causes and laboratory
investigations of thyrotoxicosis
62. 3.3.6: Luigi Bartalena: Anti-thyroid drug treatment for thyrotoxicosis
63. 3.3.7: Markus Luster and Michael Lassmann: Radio-iodine treatment of
hyperthyroidism
64. 3.3.8: Nancy Dugal Perrier, Orlo Clark, and Sarah B. Fisher: Surgery for
thyrotoxicosis
65. 3.3.9: Jacques Orgiazzi: Management of Graves hyperthyroidism
66. 3.3.10: Wilmar M. Wiersinga: Graves orbitopathy and dermopathy
67. 3.3.11: Dagmar Führer and Holger Jäschke: Management of toxic multinodular
goitre and toxic adenoma
68. 3.3.12: Wilmar M. Wiersinga: Management of thyrotoxicosis without
hyperthyroidism
69. 3.4: Hypothyroidism
70. 3.4.1: Massimo Tonacchera and Luca Chiovato: Clinical assessment and
systemic manifestations of hypothyroidism
71. 3.4.2: Ferruccio Santini: Causes and laboratory investigation of
hypothyroidism
72. 3.4.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Myxoedema coma
73. 3.4.4: Bijay Vaidya and Chantal Daumerie: Subclinical hypothyroidism
74. 3.4.5: Mark Gurnell, Carla Moran, and V. K. Chatterjee: Syndromes of
Resistance to Thyroid Hormone
75. 3.4.6: Birte Nygaard: Treatment of hypothyroidism
76. 3.5: Thyroid lumps
77. 3.5.1: Dagmar Führer and Holger Jäschke: Pathogenesis of nontoxic goitre
78. 3.5.2: Hans Graf and Gilberto Paz Filho: Management of nontoxic
multinodular goitre
79. 3.5.3: Laszlo Hegedüs and Finn N. Bennedbæk: Management of the single
thyroid nodule
80. 3.5.4: Massimo Santoro, Barbara Jarzab, Jolanta Krajewska, and Dagmara
Rusinek: Pathogenesis of thyroid cancer
81. 3.5.5: Fulvio Basolo and Clara Ugolini: Pathology of thyroid cancer
82. 3.5.6: Corin Badiu and Ruxandra Dobrescu: Papillary, follicular, and
anaplastic thyroid carcinoma and lymphoma
83. 3.5.7: Friedhelm Raue and Karin Frank-Raue: Medullary thyroid carcinoma
84. 4. Parathyroid, calcium, and bone metabolism
85. 4.1: David Goltzman and Geoffrey N. Hendy: Parathyroid anatomy, hormone
synthesis, secretion, action, and receptors
86. 4.2: Claudio Marcocci, Federica Saponaro, and Filomena Cetani:
Hypercalcaemia
87. 4.3: John P. Bilezikian: Primary hyperparathyroidism
88. 4.4: Dolores Shoback and Muriel Babey: Familial Hypocalciuric Hypercalcemia
Types 1-3 and Neonatal Severe Primary Hyperparathyroidism
89. 4.5: Rajesh Thakker, Bart Clarke, and Fadil M. Hannan: Hypocalcaemic
disorders, hypoparathyroidism, and pseudohypoparathyroidism
90. 4.6: Paul D. Miller and Michael Pazianas: Bones and the Kidney-The
Practical Conundrum: Distinguishing Between Osteoporosis and the Bone
Diseases that Accompany Chronic Renal Failure
91. 4.7: Laleh Ardeshirpour, Thomas O. Carpenter, and Cemre Robinson:
Hypercalcaemic and hypocalcaemic syndromes in children
92. 4.8: Richard Eastell: Osteoporosis
93. 4.9: Graham R. Williams, J. H. Duncan Bassett, Bernard Freudenthal, and
Laura M. Watts: Thyroid disorders and bone disease
94. 4.10: Socrates E. Papapoulos: Paget s disease of bone
95. 4.11: Michael P. Whyte: Rickets and osteomalacia (acquired and heritable
forms)
96. 4.12: Gherardo Mazziotti, Ernesto Canalis, and John P. Bilezikian:
Glucocorticoid-induced osteoporosis
97. 5. The adrenal gland and endocrine hypertension
98. 5.1: Peter Guest: Adrenal imaging
99. 5.2: Fausto Palazzo and Radu Mihai: Adrenal surgery
100. 5.3: Irina Bancos, Massimo Terzolo, and Wiebke Arlt: Adrenal incidentaloma
101. 5.4: Jérôme Bertherat, Rossella Libè, and Anne Jouinot: Adrenocortical
cancer
102. 5.5.1: Eamonn R. Maher and Ruth T Casey: Genetics of phaeochromocytomas,
paragangliomas, and neuroblastoma
103. 5.5.2: Henri Timmers: Management of phaeochromocytoma and paragagnlioma
104. 5.6.1: Maria Christina Zennaro, Fabio Fernandes-Rosa, and Sheerazed
Boulkroun: Genetics of primary aldosteronism and other steroid-related
causes of endocrine hypertension
105. 5.6.2: Morris Brown and Will Drake: Management of primary aldosteronism
106. 5.7: John Newell-Price: Cushing s syndrome
107. 5.8.1: Li Chan and Shwetha Ramachandrappa: Genetics of Adrenal
Insufficiency
108. 5.8.2: Wiebke Arlt: Management of Adrenal Insufficiency
109. 5.9.1: Nils P. Krone: Genetics of congenital adrenal hyperplasia
110. 5.9.2: Richard J. Auchus: Modern management of congenital adrenal
hyperplasia and prospects for the future
111. 6. Neuroendocrine tumours and genetic disorders
112. 6.1: Guido Rindi and Rajaventhan Srirajaskanthan: Overview and
Pathophysiology of Neuroendocrine Neoplasms
113. 6.2: Whaljit Dhillo and Paul Bech: Neuroendocrine tumour markers
114. 6.3: Rajaventhan Srirajaskanthan, Martyn E. Caplin, and Dominique Clement:
Carcinoid syndrome
115. 6.4.1: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor: Lung
neuroendocrine tumours
116. 6.4.2: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor:
Non-functioning pancreatic neuroendocrine tumours
117. 6.5: Christos Toumpanakis and Martyn E. Caplin: Gastrinoma
118. 6.6: Ashley Grossman and Ingrid YF Mak: Insulinoma and hypoglycaemia
119. 6.7: Karim Meeran: Glucagonoma
120. 6.8: Alia Munir: Vasointestinal Polypeptide Secreting Tumours
121. 6.9: John Wass: Somatostatinoma
122. 6.10: Prakash Manoharan: Imaging neuroendocrine tumours of the
gastrointestinal tract/gastroenteropancreatic neuroendocrine tumours
(GEP-NET)
123. 6.11: Rajesh V. Thakker: Multiple endocrine neoplasia type 1
124. 6.12: Electron Kebebew, Douglas Wiseman, and Mustapha El Lakis: Multiple
endocrine neoplasia type 2a and 2b
125. 6.13: Eamonn R. Maher and Ruth T. Casey: Familial syndromes and genetic
causes of paraganglioma and phaeochromocytoma
126. 6.14: Constantine A. Stratakis and Fabio Faucz: Carney s complex
127. 6.15: Michael A. Levine and Steven A. Lietman: Molecular and Clinical
Characteristics Of the McCune-Albright Syndrome
128. 6.16: Charis Eng, Lamis Yehia, and Shreya Malhotra: Cowden syndrome
129. 7. Growth and development during childhood and adolescence
130. 7.1: Growth and its Disorders
131. 7.1.1: Gary Butler: Recognising Normal and Disordered Growth
132. 7.1.2: Alexander A. L. Jorge, Fernanda A. Correa, and Renata C. Scalco:
Disorders of the GH-IGF Axis
133. 7.1.3: Anita Hokken-Koelega: Short stature in children born small for
gestational age
134. 7.1.4: Steve Chernausek and Minu George: Growth Disorders with no defined
aetiology
135. 7.1.5: Lars Savendahl and Emelie Benji: Tall Stature
136. 7.2: Sex Development
137. 7.2.1: Olaf Hiort and Ralf Werner: Sex Determination and Differentiation
138. 7.2.2: S. Faisal Ahmed and Salma R. Ali: Disorders of Sex Development (DSD)
in the newborn
139. 7.2.3: Alan Rogol and John Fuqua: Recognising Normal and Disordered
Pubertal Development
140. 7.2.4: Alan Rogol and John Fuqua: Pubertal Delay and Hypogonadism
141. 7.2.5: Julianne Leger and Jean-Claude Carel: Precocious Puberty
142. 7.3: Helena Gleeson and Rohana Wright: Transition In Endocrinology
143. 8. Female endocrinology and pregnancy
144. 8.1: Normal female endocrinology and ovarian disorders
145. 8.1.1: Chris McCartney and John Marshall: Neuroendocrinology of
reproduction: the role of hypothalamus and pituitary
146. 8.1.2: Terhi Piltonen and Juha Tapanainen: Ovarian and uterine development
from fetal life to puberty
147. 8.1.3: Gurkan Bozdag, Baris Ata, and Engin Türkgeldi: Menstrual cycle and
ovulation
148. 8.2: Evaluation of the female patient with suspected reproductive endocrine
disorders
149. 8.2.1: Channa Jayasena, Steve Franks, and Rachel Roberts: Clinical
evaluation of patient with suspected reproductive endocrine disorders
150. 8.2.2: Daniel Dumesic and Zain Al-Safi: Laboratory evaluation
151. 8.3: Reproductive endocrine disorders
152. 8.3.1: Sarah L. Berga: Disorders of gonadotrophin secreton
153. 8.3.2: Julian R. E. Davis and Agnieszka Swiecicka: Hyperprolactinaemia
154. 8.3.3: Deepthi Lavu, Radha Indusekhar, and Shaughn O'Brien: Premenstrual
syndrome
155. 8.4: Polycystic ovary syndrome and other androgen excess disorders
156. 8.4.1: Bulent Yildiz and Sezcan Mumusoglu: Polycystic ovary syndrome:
definitions, phenotypes, prevalence and genetics
157. 8.4.2: R Jeffrey Chang: Polycystic ovary syndrome: reproductive aspects
158. 8.4.3: David Ehrmann and Susan Sam: Polycystic ovary syndrome: metabolic
aspects
159. 8.4.4: Duarte Pignatelli, Ricardo Azziz, and Bulent Yildiz: Polycystic
ovary syndrome: Hirsutism
160. 8.5: Female hypogonadism and menopause
161. 8.5.1: Ephia Yasmin and Gerard S. Conway: Female hypogonadism: premature
ovarian insufficiency
162. 8.5.2: Dimitrios G. Goulis, Stavroula A. Paschou, and Panagiotis
Anagnostis: Female hypogonadism: Endocrinology of the menopause and hormone
replacement therapy
163. 8.6: Female infertility
164. 8.6.1: Adam Balen and Susie Jacob: Female Infertility and assisted
reproduction
165. 8.6.2: Kutluk Oktay and Enes Taylan: Female infertility: fertility
preservation
166. 8.7: Hormonal contraception
167. 8.7.1: Jennifer Chin Bliss Kaneshiro: Hormonal contraception
168. 8.8: Exogenous factors and female repoductive health
169. 8.8.1: Alessandra Gambineri and Daniela Ibarra-Gasparini: Exogenous factors
and female reproductive health: common extragonadal endocrinopathies
affecting reproduction
170. 8.8.2: Siew Lim, Aya Mousa, Soulmaz Shorakae, and Lisa Moran: Exogenous
factors and female reproductive health: nutrition and reproduction
171. 8.8.3: Evy Diamanti-Kandarakis and Eleni A Kandaraki: Exogenous factors and
female reproductive health: envrionment and reproduction
172. 9. Endocrinology of pregnancy
173. 9.1: Endocrine disorders of Pregnancy
174. 9.1.1: Peter Taylor, LDKE Premawardhana, and John Lazarus: General
considerations relating to thyroid disease in pregnancy
175. 9.1.2: Kris Poppe, Flora Veltri, and David Unuane: Management of thyroid
disorders before assisted and spontaneous pregnancy
176. 9.1.3: Tim Korevaar and Robin Peeters: Thyroid disease during pregnancy
177. 9.1.4: Nobuyuki Amino and Naoko Arata: Management of thyroid disorders
after pregnancy
178. 9.1.5: A. S. Paul van Trotsenburg Nitash and Zwaveling-Soonawala: Thyroid
disorders in newborns, infants and children
179. 9.1.6: Mark Molitch and Wenyu Huang: Pituitary tumours in pregnancy
180. 9.1.7: Paul Carroll, Niki Karavitaki, and Kirstie Lithgow: Other disorders
of the pituitary and hypothalamus in pregnancy
181. 9.1.8: David Torpy, Michael O'Reilly, and Sunita De Sousa: Adrenal disease
in pregnancy
182. 9.1.9: Jeremy Cox and Stephen Robinson: Endocrine bone disease in pregnancy
183. 9.1.10: Sandra Lowe: Imaging of endocrine disorders in pregnancy
184. 10. Male Reproductive Endocrinology
185. 10.1: Normal male reproductive endocrinology
186. 10.1.1: Ilpo Huhtaniemi and Jorma Toppari: Endocrine and local regulation
of testicular hormone and sperm production
187. 10.1.2: Dirk Vanderschueren, Leen Antonio, Nari Kim, and Frank Claessens:
Sex steroid actions in the Male
188. 10.2: Evaluation of the male patient with suspected hypogonadism and/or
infertility
189. 10.2.1: Bradley Anawalt: Clinical evaluation
190. 10.2.2: Jean-Marc Kaufman: Endocrine evaluation
191. 10.2.3: Jackson Kirkman-Brown and Sarah J Conner: Diagnostic Semen analysis
192. 10.3: Male reproductive endocrine disorders
193. 10.3.1: Claus H. Gravholt: Klinefelter s syndrome
194. 10.3.2: Adult Hypogonadism: Aetiology
195. 10.3.2.1: Alvin Matsumoto and Radhika Narla: Etiology of Hypogonadism
196. 10.3.2.2: Giovanni Corona, Mario Maggi, and Giulia Rastrelli: Types of
Treatments
197. 10.3.2.3: Michael Zitzmann: Gonadotrophin induction of spermatogenesis
198. 10.3.2.4: Shehzad Basaria and Thiago Gagliano-Juca: Male Hypogonadism:
Benefits of Testosterone Treatment
199. 10.3.2.5: Adrian Dobs and Swaytha Yalamanchi: Risks of T Treatment
200. 10.3.3: Herman J. Tournaye and Biljana Popovic-Todorovic: Management of
Idiopathic male infertility
201. 10.3.4: Mathis Grossmann, B. Yeap, and Gary Wittert:
Hypothalamo-pituitary-testicular axis fucntion in systemic diseases and
effects of medications
202. 10.3.5: Vincenzo Rochira, Antonio R. M. Granata, and Cesare Carani:
Management of sexual dysfunction
203. 10.3.6: Stephanie Page and Maritza Farrant: Hormonal male contraception
204. 10.3.7: Glenn Braunstein: Gynaecomastia
205. 10.4: Exogenous factors and male reproductive health
206. 10.4.1: Jorma Toppari: Environmental influences on male reproductive health
207. 10.4.2: David Handelsman: Androgen Misuse and Abuse
208. 11. Management of the Transgender Patient
209. 11.1: Jon Arcelus and Walter Bouman: Introduction to Transgender and Gender
Diverse People
210. 11.2: Daniel Klink: Endocrine Treatment of Transgender Youth
211. 11.3: Vin Tangpricha and Craig Sineath: Hormone Therapy in transgender
women
212. 11.4: Guy T'Sjoen and Justine Defreyne: Hormone therapy in transgender men
213. 11.5: Chloë De Roo and Guy T'Sjoen: Fertility Options for Transgender
Persons
214. 12. Endocrine Responses to Systemic Diseases or Substance Use
215. 12.1: Endocrinology of systemic disease
216. 12.1.1: David Henley, Thomas Upton, and Stafford L. Lightman: The endocrine
response to stress
217. 12.1.2: Greet Van den Berghe and Lies Langouche: Endocrinology in the
critically ill
218. 12.1.3: David Johnson, Melissa Nataatmadja, and Yeoungjee Cho: Hormones and
the kidney
219. 12.1.4: Jacob George and Mohammed Eslam: The endocrinology of liver disease
220. 12.1.5: Steven K. Grinspoon and Takara Stanley: Endocrine abnormalities in
HIV infection
221. 12.1.6: Karen Miller: The endocrinology of anorexia nervosa
222. 12.2: Endocrine Complications of Substance Misuse
223. 12.2.1: Marc Walter and Margit Proescholdt: Endocrinology and alcohol
224. 12.2.2: Peter Sonksen and Richard Holt: Use and abuse of
performance-enhancing hormones in sport
225. 12.2.3: Ashley Grossman, Eleni Armeni, and Bernard Khoo: Effect of Opioids
on Adrenal and Reproductive Endocrinology
226. 13. Endocrinology of cancer
227. 13.1: Endocrine Disorders Caused by Cancer or its Treatment
228. 13.1.1: Thomas Papathomas and Vania Nose: Metastatic Disease in Endocrine
Organs
229. 13.1.2: David W. Ray: Paraneoplastic endocrine syndromes
230. 13.1.3: Claire Higham and Rob Murray: Long-term endocrine sequelae of
cancer therapy
231. 13.1.4: Carla Moran: Endocrine complications of biological cancer therapies
232. 13.2: Hormonal therapy for breast and prostatic cancers
233. 13.2.1: Rob Clarke and Alice Greenhalgh: The breast: lactation and breast
cancer as an endocrine disease
234. 13.2.2: Amna Sheri and Laura Morrison: Endocrine treatment of breast cancer
235. 13.2.3: Irina A. Vasilevskaya, Matthew J. Schiewer, and Karen E. Knudsen:
Hormonal Therapy for Prostate Cancer: Molecular basis of efficacy and
therapeutic bypass
236. 14. Obesity, lipids, and metabolic disorders
237. 14.1: Obesity
238. 14.1.1: Anthony Coll: The Physiology of Bodyweight Regulation
239. 14.1.2: Adrian Bauman: Obesity as a Public Health Problem
240. 14.1.3: Rachel Batterham and Friedrich Jassil: Medical Complications of
Obesity
241. 14.1.4: John Wilding and Jonathan Lim: Dietary and Medical Management of
Obesity
242. 14.1.5: Francesco Rubino, Vivian Anastasiou, Luca Ferraro, Dalal Qanaq, and
Ghassan Chamseddine: Metabolic Surgery
243. 14.1.6: Sadaf Farooqi: Assessment of Obesity in Children
244. 14.1.7: Russell Viner and Billy White: Management of Obesity in Children
and Young People
245. 14.1.8: Nick Finer: Planning obesity care pathways
246. 14.2: Lipoprotein metabolism and dyslipidaemia
247. 14.2.1: Bo Angelin and Paolo Parini: Lipoprotein metabolism
248. 14.2.2: Stefano Romeo, Bo Angelin, and Paolo Parini: Genetic forms of
dyslipidaemia
249. 14.3: Other metabolic disorders
250. 14.3.1: Khalid Hussain and Sonya Galcheva: Hyperinsulinaemic Hypoglycaemia
251. 14.3.2: Phillip Gorden and Noemi Malandrino: Autoimmune Hypoglycaemia
252. 14.3.3: Robin H. Lachmann: Disorders of carbohydrate metabolism
253. 14.3.4: Yves Deugnier and Edouard Bardou-Jacquet: Haemochromatosis And
Other Inherited Diseases Of Iron Metabolism
254. 14.3.5: Michael N. Badminton and Danja Schulenburg-Brand: The porphyrias
255. 15. Diabetes mellitus
256. 15.1: Introduction to Diabetes Mellitus
257. 15.1.1: Shanta Persaud and Peter Jones: Physiology of glucose homeostasis
258. 15.1.2: Stephen Colagiuri and Crystal Man Ying Lee: Classification and
diagnosis of diabetes mellitus
259. 15.2: Aetiopathogenesis and Diagnosis of Type 1 Diabetes
260. 15.2.1: Elizabeth J. Mayer-Davis and Daria Igudesman: Epidemiology and
Public Health
261. 15.2.2: Augustin Brooks: Presentation and Natural History
262. 15.2.3: Richard Oram, Susan Wong, and Ayat Bashir: Pathogenesis
263. 15.3: Aetiopathogenesis and Diagnosis of Type 2 Diabetes
264. 15.3.1: Sarah Wild and Jackie Price: Epidemiology and Public Health
265. 15.3.2: Roy Taylor: Presentation and Natural History
266. 15.3.3: Mark Walker, Xuefei Yu, and Amalia Gastaldelli: Pathogenesis
267. 15.4: Non Type 1, Non Type 2 Diabetes
268. 15.4.1: Katherine Owen: Diagnosis of non type 1, non type 2 forms of
diabetes
269. 15.5: Principles of Management of Diabetes
270. 15.5.1: Simon Heller and Jackie Elliott: Structured Education
271. 15.5.2: John Pickup and Nick Oliver: Glucose Monitoring and Sensing
272. 15.5.3: Pratik Choudhary and Peter Jacob: Insulins and insulin delivery
devices
273. 15.5.4: Clifford Bailey and Melanie Davies: Non-insulin glucose lowering
agents
274. 15.5.5: Stephanie Amiel: Hypoglycaemia in the treatment of diabetes
mellitus
275. 15.6: Evidence-based Management of Type 1 Diabetes
276. 15.6.1: Peter Hammond and Fiona Campbell: Strategies for management of type
1 diabetes
277. 15.6.2: Christel Hendrieckx and Jane Speight: Psychological and Behavioural
Aspects of Type 1 Diabetes Management
278. 15.6.3: Colin Dayan and Danijela Tatovic: Immunotherapy for type 1 diabetes
279. 15.6.4: Peter Senior, Martin Drage, Anneliese Flatt, and Chris Callaghan:
Transplantation (islet and solid organ)
280. 15.7: Evidence-based Prevention and Management of Type 2 Diabetes
281. 15.7.1: Peter Winocour and Sagen Zac-Varghese: Strategies for management of
type 2 diabetes
282. 15.7.2: Jane Speight and Tim Skinner: Psychological and Behavioural Aspects
of Type 2 Diabetes Management
283. 15.7.3: Kamiesh Khunti and Nitin Narayan Gholap: Type 2 diabetes in
different ethnic groups
284. 15.7.4: Nicholas Wareham: Prevention of Type 2 Diabetes
285. 15.8: Emerging Approaches to Restoring Euglycaemia in Diabetes
286. 15.8.1: Michael White, Timothy J. Kieffer, and Cara Ellis: Regenerative
medicine for diabetes
287. 15.8.2: Roman Hovorka and Charlotte Boughton: Closed loop
288. 15.9: Emergency and Hospital management of Diabetes
289. 15.9.1: Ketan Dhatariya: Hyperglycaemic Emergencies
290. 15.9.2: Gerry Rayman: Management of the inpatient with diabetes mellitus
291. 15.9.3: Greet Van Den Berghe and Jan Gunst: Care of diabetes in ICU and
peri-sugery
292. 15.10: Specialised Management of Other forms of Diabetes
293. 15.10.1: Andrew Hattersley, Kashyap Patel, and Rachel Besser: Monogenic
forms of diabetes resulting from beta cell dysfunction
294. 15.10.2: Anna Stears, David B. Savage, and Stephen O'Rahilly:
Lipodystrophies and severe insulin resistance
295. 15.10.3.1: Phil Weston: Diabetes Secondary to Pancreatic Disease
296. 15.10.3.2: Jeremy Tomlinson: Diabetes Secondary to Endocrine Disorders
297. 15.10.4: Helen Murphy and Jennifer M Yamamoto: Diabetes in Pregnancy
298. 15.11: Psychiatry and Diabetes
299. 15.11.1: Khalida Ismail, Christopher Garrett, and Marietta Stadler: Type 1
diabetes and Psychiatry
300. 15.11.2: Khalida Ismail, Hermione Price, Marilia Calcia, Calum Moulton, and
Clare Whicher: Type 2 diabetes and Psychiatry
301. 15.12: Microvascular Complications of Diabetes
302. 15.12.1: Angela Shore: Pathogenesis of Microvascular Complications
303. 15.12.2: Peter Scanlon: Retinopathy
304. 15.12.3: Luigi Gnudi and Sally Marshall: Diabetic Nephropathy
305. 15.12.4: Solomon Tesfaye and Jing Wu: Diabetic Neuropathy
306. 15.13: Macrovascular Disease in Diabetes
307. 15.13.1: Mark Kearney, Peysh Patel, and Richard Cubbon: Mechanisms of
macrovascular disease in diabetes
308. 15.13.2: Naveed Sattar: Macrovascular disease in type 2 diabetes
309. 15.13.3: John Petrie: Macrovascular disease in type 1 diabetes
310. 15.13.4: Bruno Vergès: Diabetic dyslipidaemia
311. 15.13.5: Bryan Williams: Hypertension in diabetes melli
2. 1.1: Lynn Loriaux: Endocrine Practice Fundamentals
3. 1.2: John W. Funder: Hormones and receptors: fundamental considerations
4. 1.3: Ken Siddle and Gemma Brierley: Molecular aspects of hormonal
regulation
5. 1.4: Janine A. Danks and Samantha J. Richardson: Endocrinology and
evolution: lessons from comparative endocrinology
6. 1.5: James Gibney, Indi Banerjee, and Ken Ho: Hormones Across the Lifespan
7. 1.6: Brian Keevil, Peter Trainer, and William Drake: Pituitary assessment
strategy
8. 1.7: Simon Pearce and Catherine Owen: Endocrine autoimmunity
9. 1.8: Jerome Bertherat, Anne Jouinot, and Fidéline Bonnet-Serrano: Common
Features of Endocrine Tumours
10. 1.9: Trevor Cole: Genetic Aspects of Endocrine Disease
11. 1.10: George Mastorakos, Markella Nezi, Djuro Macut, and Maria Papagianni:
Environmental Influences on Endocrine Disease
12. 1.11: Georg Brabant and H. Oster: Endocrinology, sleep and circadian
rhythms
13. 1.12: Richard Ross: Principles of Hormone replacement
14. 1.13: Jonathan Valabhji and Rochan Agha-Jaffar: Prevention in endocrinology
15. 2. Pituitary and hypothalamic diseases
16. 2.1: John Morris: Functional anatomy of the hypothalamus and pituitary
17. 2.2: Stephen G. Ball: The neurohypophysis
18. 2.3: Aetiology, pathogenesis, and management of disease of the pituitary
19. 2.3.1: Mehul T. Dattani and Louise C. Gregory: Development of the pituitary
and genetic forms of hypopituitarism
20. 2.3.2: Shlomo Melmed: Molecular pathogenesis of pituitary tumours
21. 2.3.3: Luis Syro, Kalman Kovacs, and Fabio Rotondo: Histopathology of
pituitary tumours
22. 2.3.4: Jean-Francois Bonneville, Sonia Nagi, and Iulia Potorac: Imaging of
the pituitary
23. 2.3.5: Miles J. Levy, Ragini Bhake, and Narendra Reddy: Hypopituitarism:
replacement of adrenal, thyroid, and gonadal axes
24. 2.3.6: Jens Jørgensen: Adult growth hormone deficiency
25. 2.3.7: Edward R. Laws Jr, David L. Penn, and Caroline S. Repetti: Surgery
of pituitary tumours
26. 2.3.8: Naomi Fersht and Francesca Solda: Pituitary radiotherapy
27. 2.3.9: Nicholas Tritos and Anne Klibanski: Prolactinomas and
hyperprolactinaemia (including macroprolactinaemia)
28. 2.3.10: John Wass, Peter J. Trainer, and Márta Korbonits: Acromegaly
29. 2.3.11: Nienke Biermasz and Wouter R. van Furth: Clinically nonfunctioning
pituitary tumours and gonadotropinomas
30. 2.3.12: Mark Gurnell, Olympia Koulouri, and Waiel Bashari: Thyrotropinomas
31. 2.3.13: Ann McCormack: Pituitary carcinoma
32. 2.3.14: Niki Karavitaki, Shu Teng Chai, and Shahzada Ahmed: Pituitary
incidentalomas
33. 2.4: Aetiology, pathogenesis, and management of diseases of the
hypothalamus
34. 2.4.1: Mehul Dattani, Hoong-Wei Gan, and Manuela Cerbone: Hypothalamic
dysfunction (hypothalamic syndromes)
35. 2.4.2: Niki Karavitaki: Craniopharyngiomas
36. 2.4.3: Jürgen Honegger, Ulrike Ernemann, and Rudi Beschorner: Perisellar
tumours including cysts, hamartomas, and vascular tumours
37. 2.4.4: Mark E. Molitch and Jelena Kravarusic: Lymphocytic hypophysitis and
other inflammatory conditions of the pituitary
38. 2.5: Susan M Webb, Anna Aulinas, Cristina Colom, and José Barahona: Pineal
physiology and pathophysiology, including pineal tumours
39. 3. The Thyroid
40. 3.1: Evaluation of the thyroid patient
41. 3.1.1: Robert Volpé and Clark Sawin: The history and iconography relating
to the thyroid gland
42. 3.1.2: W. Edward Visser: Biosynthesis, transport, metabolism, and actions
of thyroid hormones
43. 3.1.3: Inge Bülow Pedersen and Stig Andersen: Clinical assessment of the
thyroid patient
44. 3.1.4: Ulla Feldt-Rasmussen: Thyroid function tests and the effects of
drugs
45. 3.1.5: Robin P. Peeters and Anita Boelen: Nonthyroidal illness syndrome
46. 3.1.6: Steen Bonnema and Laszlo Hegedüs: Thyroid imaging: nuclear medicine
techniques
47. 3.1.7: Laszlo Hegedüs and Finn N. Bennedbæk: Thyroid imaging: nonisotopic
techniques
48. 3.1.8: Mark P. J. Vanderpump: Epidemiology of thyroid disease and swelling
49. 3.2: Aetiology of thyroid disorders
50. 3.2.1: Terry Davies, Francesca Menconi, and Yaron Tomer: The complex
genetics of thyroid disease
51. 3.2.2: Josef Köhrle: Environmental factors
52. 3.2.3: Michael B. Zimmermann: Iodine deficiency disorders
53. 3.2.4: Shunichi Yamashita, Furio Pacini, and Rossella Elisei:
Radiation-induced thyroid disease
54. 3.2.5: Anthony P. Weetman: Autoimmune thyroid disease
55. 3.2.6: Elizabeth N. Pearce and Alan Farwell: Thyroiditis
56. 3.3: Thyrotoxicosis and related disorders
57. 3.3.1: Claudio Marcocci and Filomena Cetani: Clinical assessment and
systemic manifestations of thyrotoxicosis
58. 3.3.2: Annie W. C. Kung and C.L. Cheung: Thyrotoxic periodic paralysis
59. 3.3.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Thyrotoxic storm
60. 3.3.4: Simon Pearce: Subclinical hyperthyroidism
61. 3.3.5: Francesco Latrofa and Paolo Vitti: Causes and laboratory
investigations of thyrotoxicosis
62. 3.3.6: Luigi Bartalena: Anti-thyroid drug treatment for thyrotoxicosis
63. 3.3.7: Markus Luster and Michael Lassmann: Radio-iodine treatment of
hyperthyroidism
64. 3.3.8: Nancy Dugal Perrier, Orlo Clark, and Sarah B. Fisher: Surgery for
thyrotoxicosis
65. 3.3.9: Jacques Orgiazzi: Management of Graves hyperthyroidism
66. 3.3.10: Wilmar M. Wiersinga: Graves orbitopathy and dermopathy
67. 3.3.11: Dagmar Führer and Holger Jäschke: Management of toxic multinodular
goitre and toxic adenoma
68. 3.3.12: Wilmar M. Wiersinga: Management of thyrotoxicosis without
hyperthyroidism
69. 3.4: Hypothyroidism
70. 3.4.1: Massimo Tonacchera and Luca Chiovato: Clinical assessment and
systemic manifestations of hypothyroidism
71. 3.4.2: Ferruccio Santini: Causes and laboratory investigation of
hypothyroidism
72. 3.4.3: Leonard Wartofsky, Dorina Ylli, and Joanna Klubo-Gwiezdzinska:
Myxoedema coma
73. 3.4.4: Bijay Vaidya and Chantal Daumerie: Subclinical hypothyroidism
74. 3.4.5: Mark Gurnell, Carla Moran, and V. K. Chatterjee: Syndromes of
Resistance to Thyroid Hormone
75. 3.4.6: Birte Nygaard: Treatment of hypothyroidism
76. 3.5: Thyroid lumps
77. 3.5.1: Dagmar Führer and Holger Jäschke: Pathogenesis of nontoxic goitre
78. 3.5.2: Hans Graf and Gilberto Paz Filho: Management of nontoxic
multinodular goitre
79. 3.5.3: Laszlo Hegedüs and Finn N. Bennedbæk: Management of the single
thyroid nodule
80. 3.5.4: Massimo Santoro, Barbara Jarzab, Jolanta Krajewska, and Dagmara
Rusinek: Pathogenesis of thyroid cancer
81. 3.5.5: Fulvio Basolo and Clara Ugolini: Pathology of thyroid cancer
82. 3.5.6: Corin Badiu and Ruxandra Dobrescu: Papillary, follicular, and
anaplastic thyroid carcinoma and lymphoma
83. 3.5.7: Friedhelm Raue and Karin Frank-Raue: Medullary thyroid carcinoma
84. 4. Parathyroid, calcium, and bone metabolism
85. 4.1: David Goltzman and Geoffrey N. Hendy: Parathyroid anatomy, hormone
synthesis, secretion, action, and receptors
86. 4.2: Claudio Marcocci, Federica Saponaro, and Filomena Cetani:
Hypercalcaemia
87. 4.3: John P. Bilezikian: Primary hyperparathyroidism
88. 4.4: Dolores Shoback and Muriel Babey: Familial Hypocalciuric Hypercalcemia
Types 1-3 and Neonatal Severe Primary Hyperparathyroidism
89. 4.5: Rajesh Thakker, Bart Clarke, and Fadil M. Hannan: Hypocalcaemic
disorders, hypoparathyroidism, and pseudohypoparathyroidism
90. 4.6: Paul D. Miller and Michael Pazianas: Bones and the Kidney-The
Practical Conundrum: Distinguishing Between Osteoporosis and the Bone
Diseases that Accompany Chronic Renal Failure
91. 4.7: Laleh Ardeshirpour, Thomas O. Carpenter, and Cemre Robinson:
Hypercalcaemic and hypocalcaemic syndromes in children
92. 4.8: Richard Eastell: Osteoporosis
93. 4.9: Graham R. Williams, J. H. Duncan Bassett, Bernard Freudenthal, and
Laura M. Watts: Thyroid disorders and bone disease
94. 4.10: Socrates E. Papapoulos: Paget s disease of bone
95. 4.11: Michael P. Whyte: Rickets and osteomalacia (acquired and heritable
forms)
96. 4.12: Gherardo Mazziotti, Ernesto Canalis, and John P. Bilezikian:
Glucocorticoid-induced osteoporosis
97. 5. The adrenal gland and endocrine hypertension
98. 5.1: Peter Guest: Adrenal imaging
99. 5.2: Fausto Palazzo and Radu Mihai: Adrenal surgery
100. 5.3: Irina Bancos, Massimo Terzolo, and Wiebke Arlt: Adrenal incidentaloma
101. 5.4: Jérôme Bertherat, Rossella Libè, and Anne Jouinot: Adrenocortical
cancer
102. 5.5.1: Eamonn R. Maher and Ruth T Casey: Genetics of phaeochromocytomas,
paragangliomas, and neuroblastoma
103. 5.5.2: Henri Timmers: Management of phaeochromocytoma and paragagnlioma
104. 5.6.1: Maria Christina Zennaro, Fabio Fernandes-Rosa, and Sheerazed
Boulkroun: Genetics of primary aldosteronism and other steroid-related
causes of endocrine hypertension
105. 5.6.2: Morris Brown and Will Drake: Management of primary aldosteronism
106. 5.7: John Newell-Price: Cushing s syndrome
107. 5.8.1: Li Chan and Shwetha Ramachandrappa: Genetics of Adrenal
Insufficiency
108. 5.8.2: Wiebke Arlt: Management of Adrenal Insufficiency
109. 5.9.1: Nils P. Krone: Genetics of congenital adrenal hyperplasia
110. 5.9.2: Richard J. Auchus: Modern management of congenital adrenal
hyperplasia and prospects for the future
111. 6. Neuroendocrine tumours and genetic disorders
112. 6.1: Guido Rindi and Rajaventhan Srirajaskanthan: Overview and
Pathophysiology of Neuroendocrine Neoplasms
113. 6.2: Whaljit Dhillo and Paul Bech: Neuroendocrine tumour markers
114. 6.3: Rajaventhan Srirajaskanthan, Martyn E. Caplin, and Dominique Clement:
Carcinoid syndrome
115. 6.4.1: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor: Lung
neuroendocrine tumours
116. 6.4.2: Juan W. Valle, Kok Haw Jonathan Lim, and Wasat Mansoor:
Non-functioning pancreatic neuroendocrine tumours
117. 6.5: Christos Toumpanakis and Martyn E. Caplin: Gastrinoma
118. 6.6: Ashley Grossman and Ingrid YF Mak: Insulinoma and hypoglycaemia
119. 6.7: Karim Meeran: Glucagonoma
120. 6.8: Alia Munir: Vasointestinal Polypeptide Secreting Tumours
121. 6.9: John Wass: Somatostatinoma
122. 6.10: Prakash Manoharan: Imaging neuroendocrine tumours of the
gastrointestinal tract/gastroenteropancreatic neuroendocrine tumours
(GEP-NET)
123. 6.11: Rajesh V. Thakker: Multiple endocrine neoplasia type 1
124. 6.12: Electron Kebebew, Douglas Wiseman, and Mustapha El Lakis: Multiple
endocrine neoplasia type 2a and 2b
125. 6.13: Eamonn R. Maher and Ruth T. Casey: Familial syndromes and genetic
causes of paraganglioma and phaeochromocytoma
126. 6.14: Constantine A. Stratakis and Fabio Faucz: Carney s complex
127. 6.15: Michael A. Levine and Steven A. Lietman: Molecular and Clinical
Characteristics Of the McCune-Albright Syndrome
128. 6.16: Charis Eng, Lamis Yehia, and Shreya Malhotra: Cowden syndrome
129. 7. Growth and development during childhood and adolescence
130. 7.1: Growth and its Disorders
131. 7.1.1: Gary Butler: Recognising Normal and Disordered Growth
132. 7.1.2: Alexander A. L. Jorge, Fernanda A. Correa, and Renata C. Scalco:
Disorders of the GH-IGF Axis
133. 7.1.3: Anita Hokken-Koelega: Short stature in children born small for
gestational age
134. 7.1.4: Steve Chernausek and Minu George: Growth Disorders with no defined
aetiology
135. 7.1.5: Lars Savendahl and Emelie Benji: Tall Stature
136. 7.2: Sex Development
137. 7.2.1: Olaf Hiort and Ralf Werner: Sex Determination and Differentiation
138. 7.2.2: S. Faisal Ahmed and Salma R. Ali: Disorders of Sex Development (DSD)
in the newborn
139. 7.2.3: Alan Rogol and John Fuqua: Recognising Normal and Disordered
Pubertal Development
140. 7.2.4: Alan Rogol and John Fuqua: Pubertal Delay and Hypogonadism
141. 7.2.5: Julianne Leger and Jean-Claude Carel: Precocious Puberty
142. 7.3: Helena Gleeson and Rohana Wright: Transition In Endocrinology
143. 8. Female endocrinology and pregnancy
144. 8.1: Normal female endocrinology and ovarian disorders
145. 8.1.1: Chris McCartney and John Marshall: Neuroendocrinology of
reproduction: the role of hypothalamus and pituitary
146. 8.1.2: Terhi Piltonen and Juha Tapanainen: Ovarian and uterine development
from fetal life to puberty
147. 8.1.3: Gurkan Bozdag, Baris Ata, and Engin Türkgeldi: Menstrual cycle and
ovulation
148. 8.2: Evaluation of the female patient with suspected reproductive endocrine
disorders
149. 8.2.1: Channa Jayasena, Steve Franks, and Rachel Roberts: Clinical
evaluation of patient with suspected reproductive endocrine disorders
150. 8.2.2: Daniel Dumesic and Zain Al-Safi: Laboratory evaluation
151. 8.3: Reproductive endocrine disorders
152. 8.3.1: Sarah L. Berga: Disorders of gonadotrophin secreton
153. 8.3.2: Julian R. E. Davis and Agnieszka Swiecicka: Hyperprolactinaemia
154. 8.3.3: Deepthi Lavu, Radha Indusekhar, and Shaughn O'Brien: Premenstrual
syndrome
155. 8.4: Polycystic ovary syndrome and other androgen excess disorders
156. 8.4.1: Bulent Yildiz and Sezcan Mumusoglu: Polycystic ovary syndrome:
definitions, phenotypes, prevalence and genetics
157. 8.4.2: R Jeffrey Chang: Polycystic ovary syndrome: reproductive aspects
158. 8.4.3: David Ehrmann and Susan Sam: Polycystic ovary syndrome: metabolic
aspects
159. 8.4.4: Duarte Pignatelli, Ricardo Azziz, and Bulent Yildiz: Polycystic
ovary syndrome: Hirsutism
160. 8.5: Female hypogonadism and menopause
161. 8.5.1: Ephia Yasmin and Gerard S. Conway: Female hypogonadism: premature
ovarian insufficiency
162. 8.5.2: Dimitrios G. Goulis, Stavroula A. Paschou, and Panagiotis
Anagnostis: Female hypogonadism: Endocrinology of the menopause and hormone
replacement therapy
163. 8.6: Female infertility
164. 8.6.1: Adam Balen and Susie Jacob: Female Infertility and assisted
reproduction
165. 8.6.2: Kutluk Oktay and Enes Taylan: Female infertility: fertility
preservation
166. 8.7: Hormonal contraception
167. 8.7.1: Jennifer Chin Bliss Kaneshiro: Hormonal contraception
168. 8.8: Exogenous factors and female repoductive health
169. 8.8.1: Alessandra Gambineri and Daniela Ibarra-Gasparini: Exogenous factors
and female reproductive health: common extragonadal endocrinopathies
affecting reproduction
170. 8.8.2: Siew Lim, Aya Mousa, Soulmaz Shorakae, and Lisa Moran: Exogenous
factors and female reproductive health: nutrition and reproduction
171. 8.8.3: Evy Diamanti-Kandarakis and Eleni A Kandaraki: Exogenous factors and
female reproductive health: envrionment and reproduction
172. 9. Endocrinology of pregnancy
173. 9.1: Endocrine disorders of Pregnancy
174. 9.1.1: Peter Taylor, LDKE Premawardhana, and John Lazarus: General
considerations relating to thyroid disease in pregnancy
175. 9.1.2: Kris Poppe, Flora Veltri, and David Unuane: Management of thyroid
disorders before assisted and spontaneous pregnancy
176. 9.1.3: Tim Korevaar and Robin Peeters: Thyroid disease during pregnancy
177. 9.1.4: Nobuyuki Amino and Naoko Arata: Management of thyroid disorders
after pregnancy
178. 9.1.5: A. S. Paul van Trotsenburg Nitash and Zwaveling-Soonawala: Thyroid
disorders in newborns, infants and children
179. 9.1.6: Mark Molitch and Wenyu Huang: Pituitary tumours in pregnancy
180. 9.1.7: Paul Carroll, Niki Karavitaki, and Kirstie Lithgow: Other disorders
of the pituitary and hypothalamus in pregnancy
181. 9.1.8: David Torpy, Michael O'Reilly, and Sunita De Sousa: Adrenal disease
in pregnancy
182. 9.1.9: Jeremy Cox and Stephen Robinson: Endocrine bone disease in pregnancy
183. 9.1.10: Sandra Lowe: Imaging of endocrine disorders in pregnancy
184. 10. Male Reproductive Endocrinology
185. 10.1: Normal male reproductive endocrinology
186. 10.1.1: Ilpo Huhtaniemi and Jorma Toppari: Endocrine and local regulation
of testicular hormone and sperm production
187. 10.1.2: Dirk Vanderschueren, Leen Antonio, Nari Kim, and Frank Claessens:
Sex steroid actions in the Male
188. 10.2: Evaluation of the male patient with suspected hypogonadism and/or
infertility
189. 10.2.1: Bradley Anawalt: Clinical evaluation
190. 10.2.2: Jean-Marc Kaufman: Endocrine evaluation
191. 10.2.3: Jackson Kirkman-Brown and Sarah J Conner: Diagnostic Semen analysis
192. 10.3: Male reproductive endocrine disorders
193. 10.3.1: Claus H. Gravholt: Klinefelter s syndrome
194. 10.3.2: Adult Hypogonadism: Aetiology
195. 10.3.2.1: Alvin Matsumoto and Radhika Narla: Etiology of Hypogonadism
196. 10.3.2.2: Giovanni Corona, Mario Maggi, and Giulia Rastrelli: Types of
Treatments
197. 10.3.2.3: Michael Zitzmann: Gonadotrophin induction of spermatogenesis
198. 10.3.2.4: Shehzad Basaria and Thiago Gagliano-Juca: Male Hypogonadism:
Benefits of Testosterone Treatment
199. 10.3.2.5: Adrian Dobs and Swaytha Yalamanchi: Risks of T Treatment
200. 10.3.3: Herman J. Tournaye and Biljana Popovic-Todorovic: Management of
Idiopathic male infertility
201. 10.3.4: Mathis Grossmann, B. Yeap, and Gary Wittert:
Hypothalamo-pituitary-testicular axis fucntion in systemic diseases and
effects of medications
202. 10.3.5: Vincenzo Rochira, Antonio R. M. Granata, and Cesare Carani:
Management of sexual dysfunction
203. 10.3.6: Stephanie Page and Maritza Farrant: Hormonal male contraception
204. 10.3.7: Glenn Braunstein: Gynaecomastia
205. 10.4: Exogenous factors and male reproductive health
206. 10.4.1: Jorma Toppari: Environmental influences on male reproductive health
207. 10.4.2: David Handelsman: Androgen Misuse and Abuse
208. 11. Management of the Transgender Patient
209. 11.1: Jon Arcelus and Walter Bouman: Introduction to Transgender and Gender
Diverse People
210. 11.2: Daniel Klink: Endocrine Treatment of Transgender Youth
211. 11.3: Vin Tangpricha and Craig Sineath: Hormone Therapy in transgender
women
212. 11.4: Guy T'Sjoen and Justine Defreyne: Hormone therapy in transgender men
213. 11.5: Chloë De Roo and Guy T'Sjoen: Fertility Options for Transgender
Persons
214. 12. Endocrine Responses to Systemic Diseases or Substance Use
215. 12.1: Endocrinology of systemic disease
216. 12.1.1: David Henley, Thomas Upton, and Stafford L. Lightman: The endocrine
response to stress
217. 12.1.2: Greet Van den Berghe and Lies Langouche: Endocrinology in the
critically ill
218. 12.1.3: David Johnson, Melissa Nataatmadja, and Yeoungjee Cho: Hormones and
the kidney
219. 12.1.4: Jacob George and Mohammed Eslam: The endocrinology of liver disease
220. 12.1.5: Steven K. Grinspoon and Takara Stanley: Endocrine abnormalities in
HIV infection
221. 12.1.6: Karen Miller: The endocrinology of anorexia nervosa
222. 12.2: Endocrine Complications of Substance Misuse
223. 12.2.1: Marc Walter and Margit Proescholdt: Endocrinology and alcohol
224. 12.2.2: Peter Sonksen and Richard Holt: Use and abuse of
performance-enhancing hormones in sport
225. 12.2.3: Ashley Grossman, Eleni Armeni, and Bernard Khoo: Effect of Opioids
on Adrenal and Reproductive Endocrinology
226. 13. Endocrinology of cancer
227. 13.1: Endocrine Disorders Caused by Cancer or its Treatment
228. 13.1.1: Thomas Papathomas and Vania Nose: Metastatic Disease in Endocrine
Organs
229. 13.1.2: David W. Ray: Paraneoplastic endocrine syndromes
230. 13.1.3: Claire Higham and Rob Murray: Long-term endocrine sequelae of
cancer therapy
231. 13.1.4: Carla Moran: Endocrine complications of biological cancer therapies
232. 13.2: Hormonal therapy for breast and prostatic cancers
233. 13.2.1: Rob Clarke and Alice Greenhalgh: The breast: lactation and breast
cancer as an endocrine disease
234. 13.2.2: Amna Sheri and Laura Morrison: Endocrine treatment of breast cancer
235. 13.2.3: Irina A. Vasilevskaya, Matthew J. Schiewer, and Karen E. Knudsen:
Hormonal Therapy for Prostate Cancer: Molecular basis of efficacy and
therapeutic bypass
236. 14. Obesity, lipids, and metabolic disorders
237. 14.1: Obesity
238. 14.1.1: Anthony Coll: The Physiology of Bodyweight Regulation
239. 14.1.2: Adrian Bauman: Obesity as a Public Health Problem
240. 14.1.3: Rachel Batterham and Friedrich Jassil: Medical Complications of
Obesity
241. 14.1.4: John Wilding and Jonathan Lim: Dietary and Medical Management of
Obesity
242. 14.1.5: Francesco Rubino, Vivian Anastasiou, Luca Ferraro, Dalal Qanaq, and
Ghassan Chamseddine: Metabolic Surgery
243. 14.1.6: Sadaf Farooqi: Assessment of Obesity in Children
244. 14.1.7: Russell Viner and Billy White: Management of Obesity in Children
and Young People
245. 14.1.8: Nick Finer: Planning obesity care pathways
246. 14.2: Lipoprotein metabolism and dyslipidaemia
247. 14.2.1: Bo Angelin and Paolo Parini: Lipoprotein metabolism
248. 14.2.2: Stefano Romeo, Bo Angelin, and Paolo Parini: Genetic forms of
dyslipidaemia
249. 14.3: Other metabolic disorders
250. 14.3.1: Khalid Hussain and Sonya Galcheva: Hyperinsulinaemic Hypoglycaemia
251. 14.3.2: Phillip Gorden and Noemi Malandrino: Autoimmune Hypoglycaemia
252. 14.3.3: Robin H. Lachmann: Disorders of carbohydrate metabolism
253. 14.3.4: Yves Deugnier and Edouard Bardou-Jacquet: Haemochromatosis And
Other Inherited Diseases Of Iron Metabolism
254. 14.3.5: Michael N. Badminton and Danja Schulenburg-Brand: The porphyrias
255. 15. Diabetes mellitus
256. 15.1: Introduction to Diabetes Mellitus
257. 15.1.1: Shanta Persaud and Peter Jones: Physiology of glucose homeostasis
258. 15.1.2: Stephen Colagiuri and Crystal Man Ying Lee: Classification and
diagnosis of diabetes mellitus
259. 15.2: Aetiopathogenesis and Diagnosis of Type 1 Diabetes
260. 15.2.1: Elizabeth J. Mayer-Davis and Daria Igudesman: Epidemiology and
Public Health
261. 15.2.2: Augustin Brooks: Presentation and Natural History
262. 15.2.3: Richard Oram, Susan Wong, and Ayat Bashir: Pathogenesis
263. 15.3: Aetiopathogenesis and Diagnosis of Type 2 Diabetes
264. 15.3.1: Sarah Wild and Jackie Price: Epidemiology and Public Health
265. 15.3.2: Roy Taylor: Presentation and Natural History
266. 15.3.3: Mark Walker, Xuefei Yu, and Amalia Gastaldelli: Pathogenesis
267. 15.4: Non Type 1, Non Type 2 Diabetes
268. 15.4.1: Katherine Owen: Diagnosis of non type 1, non type 2 forms of
diabetes
269. 15.5: Principles of Management of Diabetes
270. 15.5.1: Simon Heller and Jackie Elliott: Structured Education
271. 15.5.2: John Pickup and Nick Oliver: Glucose Monitoring and Sensing
272. 15.5.3: Pratik Choudhary and Peter Jacob: Insulins and insulin delivery
devices
273. 15.5.4: Clifford Bailey and Melanie Davies: Non-insulin glucose lowering
agents
274. 15.5.5: Stephanie Amiel: Hypoglycaemia in the treatment of diabetes
mellitus
275. 15.6: Evidence-based Management of Type 1 Diabetes
276. 15.6.1: Peter Hammond and Fiona Campbell: Strategies for management of type
1 diabetes
277. 15.6.2: Christel Hendrieckx and Jane Speight: Psychological and Behavioural
Aspects of Type 1 Diabetes Management
278. 15.6.3: Colin Dayan and Danijela Tatovic: Immunotherapy for type 1 diabetes
279. 15.6.4: Peter Senior, Martin Drage, Anneliese Flatt, and Chris Callaghan:
Transplantation (islet and solid organ)
280. 15.7: Evidence-based Prevention and Management of Type 2 Diabetes
281. 15.7.1: Peter Winocour and Sagen Zac-Varghese: Strategies for management of
type 2 diabetes
282. 15.7.2: Jane Speight and Tim Skinner: Psychological and Behavioural Aspects
of Type 2 Diabetes Management
283. 15.7.3: Kamiesh Khunti and Nitin Narayan Gholap: Type 2 diabetes in
different ethnic groups
284. 15.7.4: Nicholas Wareham: Prevention of Type 2 Diabetes
285. 15.8: Emerging Approaches to Restoring Euglycaemia in Diabetes
286. 15.8.1: Michael White, Timothy J. Kieffer, and Cara Ellis: Regenerative
medicine for diabetes
287. 15.8.2: Roman Hovorka and Charlotte Boughton: Closed loop
288. 15.9: Emergency and Hospital management of Diabetes
289. 15.9.1: Ketan Dhatariya: Hyperglycaemic Emergencies
290. 15.9.2: Gerry Rayman: Management of the inpatient with diabetes mellitus
291. 15.9.3: Greet Van Den Berghe and Jan Gunst: Care of diabetes in ICU and
peri-sugery
292. 15.10: Specialised Management of Other forms of Diabetes
293. 15.10.1: Andrew Hattersley, Kashyap Patel, and Rachel Besser: Monogenic
forms of diabetes resulting from beta cell dysfunction
294. 15.10.2: Anna Stears, David B. Savage, and Stephen O'Rahilly:
Lipodystrophies and severe insulin resistance
295. 15.10.3.1: Phil Weston: Diabetes Secondary to Pancreatic Disease
296. 15.10.3.2: Jeremy Tomlinson: Diabetes Secondary to Endocrine Disorders
297. 15.10.4: Helen Murphy and Jennifer M Yamamoto: Diabetes in Pregnancy
298. 15.11: Psychiatry and Diabetes
299. 15.11.1: Khalida Ismail, Christopher Garrett, and Marietta Stadler: Type 1
diabetes and Psychiatry
300. 15.11.2: Khalida Ismail, Hermione Price, Marilia Calcia, Calum Moulton, and
Clare Whicher: Type 2 diabetes and Psychiatry
301. 15.12: Microvascular Complications of Diabetes
302. 15.12.1: Angela Shore: Pathogenesis of Microvascular Complications
303. 15.12.2: Peter Scanlon: Retinopathy
304. 15.12.3: Luigi Gnudi and Sally Marshall: Diabetic Nephropathy
305. 15.12.4: Solomon Tesfaye and Jing Wu: Diabetic Neuropathy
306. 15.13: Macrovascular Disease in Diabetes
307. 15.13.1: Mark Kearney, Peysh Patel, and Richard Cubbon: Mechanisms of
macrovascular disease in diabetes
308. 15.13.2: Naveed Sattar: Macrovascular disease in type 2 diabetes
309. 15.13.3: John Petrie: Macrovascular disease in type 1 diabetes
310. 15.13.4: Bruno Vergès: Diabetic dyslipidaemia
311. 15.13.5: Bryan Williams: Hypertension in diabetes melli