Exosome Communication - Gugulothu, Dilapathi; Khatri, Dharmendra Kumar; Vora, Lalitkumar K; Cho, William C S
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Exosome Communication: Advances in Research and Therapeutics for Health and Disease is a reference tailored for pharmaceutical scientists and covers the key qualities of exosomes as drug delivery vehicles. Exosomes are intracellular membrane-based vesicles with diverse compositions, offering advantages over other drug delivery systems like liposomes and polymeric nanoparticles due to their non-immunogenic nature. This book provides a comprehensive exploration of exosomes, starting with their history and development, understanding extracellular vesicles and biogenesis, and techniques for…mehr

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Produktbeschreibung
Exosome Communication: Advances in Research and Therapeutics for Health and Disease is a reference tailored for pharmaceutical scientists and covers the key qualities of exosomes as drug delivery vehicles. Exosomes are intracellular membrane-based vesicles with diverse compositions, offering advantages over other drug delivery systems like liposomes and polymeric nanoparticles due to their non-immunogenic nature. This book provides a comprehensive exploration of exosomes, starting with their history and development, understanding extracellular vesicles and biogenesis, and techniques for isolation and characterization. It also delves into cargo loading, release strategies, and their potential applications in diagnostics and various diseases, including antigen-specific delivery, gene delivery, and vaccine delivery, highlighting how engineering exosomes can enhance therapeutic efficacy. The book also addresses critical considerations like quality control, heterogeneity reduction, regulatory and ethical aspects, clinical trials, and scale-up manufacturing. By providing a comprehensive and detailed overview of exosome-based therapeutics' potential, "Exosome Communication: Advances in Research and Therapeutics for Health and Disease" serves as a valuable reference for those interested in exploring exosomes' applications in drug delivery and therapeutics.
Autorenporträt
Dr. Gugulothu is an Assistant Professor in the Department of Pharmaceutics, Delhi Institute of Pharmaceutical Sciences and Research, India. His doctoral dissertation work was in Pharmaceutics involved exploring nanotechnology in enhancing the biological activity of curcumin and ellagic acid independently or in combination with synthetic analogues in various diseases like malaria, diabetes, ulcerative colitis and H.pylori infection. Currently he is working on exploring natural mucilages as a pharmaceutical excipient for development of novel drug delivery systems for treatment of Parkinson's disease and diabetes, Exosome delivery, nanofibers for drug delivery, functional Graphen oxide Nanoparticles for treatment of cancer. Furthermore, he is working on development of analytical methods for APIs.