A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery - Chen, Taosheng
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Few scientists have the multidisciplinary experience needed to control all aspects of a high-throughput screening (HTS) drug discovery project. This volume integrates the knowledge of experts in biology, chemistry, informatics, instrumentation, automation, technology development, and project management. Enabling researchers in industrial and academic settings to find the most efficient way to carry a project from start to finish, this volume identifies critical targets that are of relevance to drug discovery, discusses the components of the HTS process, and provides step-by-step instructions…mehr

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Produktbeschreibung
Few scientists have the multidisciplinary experience needed to control all aspects of a high-throughput screening (HTS) drug discovery project. This volume integrates the knowledge of experts in biology, chemistry, informatics, instrumentation, automation, technology development, and project management. Enabling researchers in industrial and academic settings to find the most efficient way to carry a project from start to finish, this volume identifies critical targets that are of relevance to drug discovery, discusses the components of the HTS process, and provides step-by-step instructions for an HTS project, while also examining emerging technologies and systems.
Autorenporträt
Taosheng Chen earned a BS in biophysics and an MS in molecular cell biology from Fudan University in Shanghai, China. He received his PhD in cell and molecular biology from the University of Vermont at Burlington. Dr. Chen joined the faculty of the Department of Chemical Biology and Therapeutics and became director of the HTS Center at the St. Jude Children's Research Hospital in Memphis in 2006. His laboratory focuses on studying the regulation of transcription factors and their implications in drug metabolism and drug resistance as well as in pediatric cancers. Dr. Chen has authored more than 20 peer-reviewed articles in the areas of cancer biology, drug metabolism, signal transduction, and drug discovery technology.