Bioremediation of pesticide in soil and water is today's urgent need. By biological method it found more safer than other physical and chemical methods. Endosulfan and monocrotophos are the most popular and cheap pesticides. Now monocrotophos is partially or fully banned in many countries. Endosulfan is also now banned in many countries. But in some countries these pesticides are still in use the residues and byproducts of these pesticides are countiued the serious attention. This an attempt to develop the biodegradation technology of these pesticies.