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Cancer related fatigue is one of the most prevalent distressing cancer related symptoms, both during and after their treatment. It can have a broad impact on physical, emotional and cognitive function of the sufferers. It tends to worsen with the progression of cancer and its treatment. The evidences were showing that patients with Cancer related fatigue has a low quality of life and poor survival rate. This study shows the burden of Cancer related fatigue and contributing factors in the study area and help to take possible actions.