Tibor Hianik, Victor Ivanovich Passechnik

Bilayer Lipid Membranes. Structure and Mechanical Properties

• Gebundenes Buch

Produktbeschreibung

In Bilayer Lipid Membranes. Structure and Mechanical Properties the authors use new methods of measurement, which they have themselves developed, to present an analysis of the relation between membrane structure and viscoelastic properties, in particular in the transversal direction. Hianik and Passechnik's approach is fundamentally different from the usual one, in that they analyze lipid bilayer dynamics during various modes of deformation, arriving at a new, `three-layer' model that accounts for the great heterogeneity of biomembranes. The macroscopic parameters of membranes have been measured using a wide variety of methods, leading to a discussion of the correlations between the parameters. There is also an extensive discussion of the dynamic changes in mechanical properties of lipid bilayers in the course of conformational transition of integral proteins. During the conformational changes of proteins, the structure of a bilayer undergoes a transition, reaching a new, stable membrane state. The book is the first to present a comprehensive analysis of long-distance interaction in lipid bilayers and of molecular mechanisms of mechanoreception.
Audience: Scientists and graduate students working in biophysics, membranology, physiology, medicine, pharmacology, bioelectronics, electrochemistry, and colloid chemistry.

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Produktdetails

• Verlag: Ister Science Press Ltd. / Springer / Springer Netherlands
• Artikelnr. des Verlages: 978-0-7923-3551-1
• 1995.
• Seitenzahl: 452
• Erscheinungstermin: 31. August 1995
• Englisch
• Abmessung: 241mm x 160mm x 29mm
• Gewicht: 807g
• ISBN-13: 9780792335511
• ISBN-10: 0792335511
• Artikelnr.: 21589275

Inhaltsangabe

Introduction. 1. The Elasticity and Viscosity of Biological Membranes. 2.
The Measurement of the Elastic Modulus EBOTTOM of Lipid Bilayer Membranes
in a Transversal Direction. 3. Methods to Measure the Viscoelasticity of
Bilayer Lipid Membranes and Liposomes. 4. The Peculiarity of the Electrical
Field in Membranes and an Evaluation of their Capacitance. 5. The Bilayer
Lipid Membrane as a Viscoelastic Body. 6. The Application of the Phenomena
of the Generation of Higher Current Harmonics to the Solution of Different
Biophysical Tasks and a Comparison of Microscopic and Macroscopic
Parameters of Lipid Bilayers. 7. The Mechanical Properties of Lipid Bilayer
under Different Action. 8. The Mechanical and Thermodynamical Properties of
Lipid Bilayer due to the Incorporation and Conformational Changes of
Membrane Proteins. 9. The Distortion of the Structure of Lipid Bilayer
around Membrane Proteins and the Problems of Long-Distance Interactions.
10. The Mechanics of Lipid Bilayers and the Problems of Mechanoreception.
Epilogue. Bibliography. Index.