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Micronuclei in epithelial cells are widely used as biomarkers for monitoring genetic instability in humans. In this study, we have evaluated the buccal cells of 144 normal healthy individuals. The frequency of micronuclei was analysed and their relationship to different confounding factors (age, gender, diet and life style habits) was determined. The results show a significant increase in the observed frequency of micronuclei with respect to age. Males show a comparatively high percentage of micronuclei. Non-vegetarian diet, smoking and alcohol consumption are also suggestively significant.

Produktbeschreibung
Micronuclei in epithelial cells are widely used as biomarkers for monitoring genetic instability in humans. In this study, we have evaluated the buccal cells of 144 normal healthy individuals. The frequency of micronuclei was analysed and their relationship to different confounding factors (age, gender, diet and life style habits) was determined. The results show a significant increase in the observed frequency of micronuclei with respect to age. Males show a comparatively high percentage of micronuclei. Non-vegetarian diet, smoking and alcohol consumption are also suggestively significant.
Autorenporträt
Usha Veerachari,Asst Prof,Dept. of Life Sciences,Jain Univ,Bangalore, India has 17 yrs of teaching experience in Biological Sciences.The present work was done along with co-author Shilpa Venkatesh,Dept. of Life Sciences, Jain Univ, under the guidance of Dr. Rajeshwari N, Associate Prof,Dept. of BE Biotech,Dayananda Sagar college of Engg,Bangalore.