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This Book provides varies synthetic strategies for benzothiazepines. it consists two chapters. Chapter:1 Includes Synthesis,biological evaluation of 25 new Chalcones and all 25 Chalcones are prepared by Claisen Schmidt condensation. most of the compounds shows moderate Antimicrobial and cytotoxic activity as compared with standard drugs. chapter:2 Includes Synthesis and biological evaluation of 20 new Benzothiazepines. I hope this book will be helpfull for research