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Drug stability studies are a mainstay of current
methodological research in biostatistics. The major
focus of this book concerns a certain statistic that
plays a crucial role in constructing confidence
bounds with a constrained explanatory variable.
Although the form of the statistic is involved and
cumbersome, its exact distribution was derived.
It has been shown in this research that the
statistic of the cut-off point for the optimal value
has a very nice and simple distribution: a standard
Cauchy distribution; in fact, amazingly, it has also
been shown that this statistic is independent of a
pivotal quantity that aids in the discovery of
critical values for developing the confidence
bounds. These results shed surprising new light on
long standing knotty problems in biostatistics.
This research should be useful to researchers and
practitioners alike in all areas of Biostatistical
study, and in particular, to individuals
specializing in pharmaceutical research.
methodological research in biostatistics. The major
focus of this book concerns a certain statistic that
plays a crucial role in constructing confidence
bounds with a constrained explanatory variable.
Although the form of the statistic is involved and
cumbersome, its exact distribution was derived.
It has been shown in this research that the
statistic of the cut-off point for the optimal value
has a very nice and simple distribution: a standard
Cauchy distribution; in fact, amazingly, it has also
been shown that this statistic is independent of a
pivotal quantity that aids in the discovery of
critical values for developing the confidence
bounds. These results shed surprising new light on
long standing knotty problems in biostatistics.
This research should be useful to researchers and
practitioners alike in all areas of Biostatistical
study, and in particular, to individuals
specializing in pharmaceutical research.