The field experiment "Split application of NPK fertilizers on performance of papaya" was conducted during the year 2020-2021. The experiment was laid out in RBD Design which comprises seven treatments and four replications. Among the treatments 125 percent, 100 per cent RDF through split application shows good results in aspects of growth, yield, quality and nutrient content of leaf in papaya when compared to other treatments. Hence at different growth stages i.e., 150:125:100 N: P2O5: K2O g plant-1 in vegetative stage of 4 months, 50:100:150 N: P2O5: K2O g plant-1 in flowering to fruit set stage of 2 months, 50:25:250 N: P2O5: K2O g plant-1 in fruit development stage of 3 months at monthly intervals split application of fertilizers proved to be promising for fetching higher yield and good quality of papaya fruits according cost benefit ratio.