This book provides a comprehensive and systematic analysis of the morphodynamic process of the Changjiang River from upstream to estuary in the Anthropocene. As the longest river in China, the Changjiang River has nurtured Chinese civilization with ample natural resources for thousands of years. Evidence highlights that the Changjiang River has experienced intensive human interference and indicated dramatic changes in the Anthropocene, including “no flood in flood season, no dry in dry season” in discharge; “less flood in flood season, more dry in dry season” in sediment; riverbed shifts from accretion to erosion; lakes in the middle-lower reach turn from sediment sink to source; estuarine tidal flat exhibits self-organization characteristics and maintains the current accretion state; estuarine branches that connect to the sea show district morphodynamic patterns; and depocenters of the submerged delta indicate periodic shifts. The book stresses that dam construction upstream, practically the Three Gorges Dam, the world’s largest hydraulic engineering project, has significant influences on the hydrology and geomorphology of the middle-lower reach but has a slight effect on estuarine delta development. The geomorphological structure of the estuarine channel is dominated by local land reclamation, navigation, and dredging. This book clarifies the river-estuary morphodynamics of the Changjiang River and indicates the general features of global mega rivers under human interference as well as their own response mechanisms. This book also exhibits the potential risk of river-estuary deltas in the future, as both material and dynamics are experiencing acceleration adjustment.