5-HT4 Receptors in the Brain and Periphery

Herausgegeben:Eglen, Richard M.

• Broschiertes Buch

Produktbeschreibung

This book provides a comprehensive, up-to-date review of the distribution, pharmacology and physiology of central 5-hydroxytryptamine (5-HT)4 receptors. The 5-HT receptor subtypes exhibit a unique pharmacology, distribution and function, of which the 5-HT4 receptor has been one of the most intensively studied in recent years, both from a basic research standpoint and as a target for novel therapeutics.

Produktdetails

• Biotechnology Intelligence Unit
• Verlag: Springer / Springer Berlin Heidelberg / Springer, Berlin
• Artikelnr. des Verlages: 978-3-662-05555-7
• Softcover reprint of the original 1st ed. 1998
• Seitenzahl: 244
• Erscheinungstermin: 14. Januar 2013
• Englisch
• Abmessung: 235mm x 155mm x 14mm
• Gewicht: 377g
• ISBN-13: 9783662055557
• ISBN-10: 3662055554
• Artikelnr.: 39915535

Inhaltsangabe

1. Medicinal Chemistry of 5-HT4 Receptor Ligands.- 2. Molecular Biology of 5-HT4 Receptors.- 3. Localization of 5-HT4 Receptors in Vertebrate Brain and Their Potential Behavioral Roles.- 4. Central 5-HT4 Receptors: Electrophysiology.- 5. Neurochemical Consequences Following Pharmacological Manipulation of Central 5-HT4 Receptors.- 6. 5-Hydroxytryptamine and Human Heart Function: The Role of 5-HT4 Receptors.- 7. 5-HT4 Receptors in Gastrointestinal Tract.- 8. 5-HT4 Receptors in Lower Urinary Tract Tissues.- 9. The 5-HT4 Receptor in the Adrenal Gland.- 10. Therapeutic Applications of 5-HT4 Receptor Agonists and Antagonists.