The progressive increase in the incidence of cancer during the last decades has turned it into a health problem. In the oral cavity they manifest themselves as whitish lesions; within these, leukoplakia is one of the most frequent potentially malignant disorders. The study of these disorders could be supported by the use of morphometry. There were relationships between the morphometric variables, except for the circularity of the nucleus. Significant differences were shownsignificant differences between the mean values of the variables nucleus area/cytoplasm area ratio, in the cytoplasmic area variable; the rest of the variables did not show differences in their mean values.