I. Cellular Interactions in Inflammatory Processes.- 1 Cellular Interactions Regulating Inflammation: Activation of T Lymphocytes at Inflammatory Sites and Their Role in Perpetuating Chronic Inflammation.- 2 Triggering and Activation of Human Neutrophils: Two Aspects of the Response to Transmembrane Signals.- 3 Neutrophil Emigration: Quantitation, Kinetics, and the Role of Mediators.- 4 The Role of Endothelium in Chronic Inflammation.- II. Peptide Mediators of Inflammation.- 5 Peptide Mediators of Inflammation: An Overview.- 6 Interleukin-1: Biology and Molecular Biology.- 7 Structure—Function Relations for the Interleukin-2 Receptor.- 8 Cachectin (Tumor Necrosis Factor): A Macrophage Protein that Induces a Catabolic State and Septic Shock in Infected Animals.- III. Biosynthesis and Release of Lipid Mediators of Inflammation.- 9 Arachidonic Acid Metabolism in Tissue Injury.- 10 Lipoxygenase Metabolites: Chemistry and Biochemistry.- IV. Molecular Intermediates in Signal Transductions.- 11 Guanine Nucleotide Regulatory Proteins in Inflammatory and Immune Responses.- 12 Regulation of Phosphoinositide Breakdown.- 13 Regulation of Protein Kinase C by Sphingosine/Lysosphingolipids.- 14 Regulation of Inositol Trisphosphate Formation and Action.- V. Receptors and Signal Transduction Processes Involved in Inflammation.- 15 Molecular Properties of Leukocyte Receptors for Leukotrienes.- 16 LTD4 Receptors and Signal Transduction Processes.- 17 Characterization of Thromboxane A2/Prostaglandin H2 Receptors.- 18 Chemoattractant Receptors and Signal Transduction Processes.- 19 The Molecular Biology of the Human Interleukin-2 Receptor.- VI. The Role of Phospholipases in Inflammation.- 20 Some Novel Phospholipase C Activities: Actions on Phosphatidylcholine and onPhosphatidylinositol—Glycans as Anchors for Membrane Proteins and as Precursors for Possible Insulin Mediators.- 21 Enzymatic Mechanisms and Inhibition of Phospholipase A2: From Manoalide to the Lipocortins.- 22 Molecular Mechanism of Regulation of Cellular Phospholipases.- 23 The Metabolism of Inositol Phosphates.