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This book covers about efficacy of Bacillus subtilis var. amyloliquefaciens strain FZB24 Plant growth promoting rhizobacteria against Alternaria solanii,Phytophthora infestans in tomato and describes about mode of action of Bacillus subtilis and Explains about control of different fungal diseases by using bio-fungicide. It clearly indicated about optimum concentration of Bacillus sp against different fungal and bacterial diseases. It explains about difference between effect of bio-fungicides and fungicides in open field condition. Finally it gives a idea about efficacy of Bacillus subtilis var. amyloliquefaciens strain FZB24 Plant growth promoting rhizobacteria against Alternaria solanii,Phytophthora infestans in tomato to the researchers who wants to work in this topic in future.