The origin of Universe and end state of some stars are identical. In the sense stars end in a singularity and Universe begins with it. The possibility of a multiverse as well exists. Eternal inflation, multiverse, Schwartzchild's black holes and theory of entropy are related. Energetics of the Universe is evaluated critically and a connection has been established between Newtonian laws and the laws of thermodynamics. Osmosis is explained with a thistle funnel osmometer. Osmometer though a non-living system gives an impression that osmosis itself is a process associated with life. The first and third laws of Newton have a consequence to the fourth law of thermodynamics. A distinction between hydraulic continuity and thermodynamic continuity is made; this knowledge has practical uses to plants as well as humans. A commentary on philosophy and science of self is interesting. The loop of self in living system like a Cuscuta vine is identified experimentally. An infinite regress of reasoning in origin of life or Universe has been found.
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