Insights into Human Neurodegeneration: Lessons Learnt from Drosophila
-
- Hardcover
- Taschenbuch ausgewählt
- eBook
-
Sprache:Englisch
97,99 €
inkl. gesetzl. MwSt.,
Beschreibung
Produktdetails
Einband
Taschenbuch
Erscheinungsdatum
22.01.2021
Abbildungen
X, 467 p. 48 illus., 43 illus. in color.
Herausgeber
Mousumi Mutsuddi + weitereVerlag
Springer SingaporeSeitenzahl
467
Maße (L/B/H)
23,5/15,5/2,5 cm
Gewicht
822 g
Auflage
1st ed. 2019
Sprache
Englisch
ISBN
978-981-3299-13-9
This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from
Drosophila
model
,
in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions
.
Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from
Drosophila
about Alzheimer's, Parkinson’s, Spinomuscular Atrophy, Huntington’s diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of
Drosophila
for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of
Drosophila
as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from
Drosophila
and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.
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