Are we related to Neanderthals? Where did SARS come from? Which part of our genome is evolving the fastest? How does one detect genes borrowed from other organisms? These are some of the questions that can be answered by statistical and computational analysis of genetic data, and are the vehicle for this self-contained and entertaining introduction to computational genomics, based on a successful course taught at UC Davis. The case-studies approach with Matlab demos provides a painless and enjoyable way to learn how to analyze genomic data first-hand.
Are we related to Neanderthals? Where did SARS come from? Which part of our genome is evolving the fastest? How does one detect genes borrowed from other organisms? These are some of the questions that can be answered by statistical and computational analysis of genetic data, and are the vehicle for this self-contained and entertaining introduction to computational genomics, based on a successful course taught at UC Davis. The case-studies approach with Matlab demos provides a painless and enjoyable way to learn how to analyze genomic data first-hand.Hinweis: Dieser Artikel kann nur an eine deutsche Lieferadresse ausgeliefert werden.
Nello Cristianini is a Professor of Artificial Intelligence, University of Bristol.
Inhaltsangabe
Prologue (in praise of cells); 1. The first look at a genome (sequence statistics); 2. All the sequence's men (gene finding); 3. All in the family (sequence alignment); 4. The boulevard of broken genes (hidden Markov models); 5. Are Neanderthals among us? (variation within and between species); 6. Fighting HIV (natural selection at the molecular level); 7. SARS: a post-genomic epidemic (phylogenetic analysis); 8. Welcome to the hotel Chlamydia (whole genome comparisons); 9. The genomics of wine-making (analysis of gene expression); 10. A bed-time story (identification of regulatory sequences); Appendix.Prologue (In praise of cells); 1. The first look at a genome (sequence statistics); 2. All the sequence's men (gene finding); 3. All in the family (sequence Alignment); 4. The boulevard of broken genes (hidden Markov models); 5. Are Neanderthals among us? (variation within and between species); 6. Fighting HIV (natural selection at the molecular level); 7. SARS: a post-genomic epidemic (phylogenetic analysis); 8. Welcome to the hotel Chlamydia (whole genome comparisons); 9. The genomics of wine-making (Analysis of gene expression); 10. A bed-time story (identification of regulatory sequences); A. The appendix.
Prologue (in praise of cells); 1. The first look at a genome (sequence statistics); 2. All the sequence's men (gene finding); 3. All in the family (sequence alignment); 4. The boulevard of broken genes (hidden Markov models); 5. Are Neanderthals among us? (variation within and between species); 6. Fighting HIV (natural selection at the molecular level); 7. SARS: a post-genomic epidemic (phylogenetic analysis); 8. Welcome to the hotel Chlamydia (whole genome comparisons); 9. The genomics of wine-making (analysis of gene expression); 10. A bed-time story (identification of regulatory sequences); Appendix.Prologue (In praise of cells); 1. The first look at a genome (sequence statistics); 2. All the sequence's men (gene finding); 3. All in the family (sequence Alignment); 4. The boulevard of broken genes (hidden Markov models); 5. Are Neanderthals among us? (variation within and between species); 6. Fighting HIV (natural selection at the molecular level); 7. SARS: a post-genomic epidemic (phylogenetic analysis); 8. Welcome to the hotel Chlamydia (whole genome comparisons); 9. The genomics of wine-making (Analysis of gene expression); 10. A bed-time story (identification of regulatory sequences); A. The appendix.
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