Novel Methods & Applications of Tropane Alkaloids and Proline Analogs
Ramakrishna Edupuganti
Broschiertes Buch

Novel Methods & Applications of Tropane Alkaloids and Proline Analogs

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Organic/Medicinal chemistry plays a vital role in drug discovery and development. Synthetic organic chemistry is a powerful tool to create medicinally useful molecules by rational structure-based drug discovery approach. Innovative methodologies are greatly needed to overcome synthetic challenges and produce biologically active molecules efficiently. This book describes such novel and practical methods: (i) the development of new methodologies for the asymmetric synthesis of homotropinone and tropane alkaloids such as cocaine using enantiopure sulfinimines; and (ii) Stereoselective synthesis o...