The effect of climate conditions the environment in which cattle live and reproduce, making milk production and quality complex. This situation modifies important factors such as the availability/quality of water and feed. In response to the adverse effects, cattle modify their physiological and behavioral mechanisms in order to maintain their body temperature in a normal range. This study describes the relationship between the variables precipitation, temperature, temperature and humidity index (TIH) with milk production of the years 2011 and 2014 in the tropics (TS) and humid tropics (TH) and fat percentage of the years 2015 and 2016 in the TS. The historical records of production (Pd) and quality correspond to 18 CREL (milk collection and cooling centers), distributed in different life zones of the municipality of Olanchito, department of Yoro in Honduras. During the period analyzed, an irregular distribution of rainfall, an increase in temperatures and high rainfall (Pt) wereobserved, causing a seasonal vulnerability of production.