Role of Ionic Liquids in drug discovery and development
Application to bioequivalence studies
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Ionic liquids (ILs) are ionic, non-molecular solvents with melting points below 100 C. The most notable properties include their negligible vapor pressure at room temperature, high thermal stability, and variable viscosity. Their miscibility in water and organic solvents can be controlled by selecting the cation/anion combination or by incorporating certain functional groups in the IL molecule. In addition, they possess a multitude of tunable physicochemical properties. There has been enormous interest in the development of analytical methods that exploit the unique physicochemical properties ...
Ionic liquids (ILs) are ionic, non-molecular solvents with melting points below 100 C. The most notable properties include their negligible vapor pressure at room temperature, high thermal stability, and variable viscosity. Their miscibility in water and organic solvents can be controlled by selecting the cation/anion combination or by incorporating certain functional groups in the IL molecule. In addition, they possess a multitude of tunable physicochemical properties. There has been enormous interest in the development of analytical methods that exploit the unique physicochemical properties of ILsSpecial features of ionic liquids Low-vapor pressure High viscosity Dual natural polarity Good thermal stability A wide range of miscibility with water and other organic solvents Environmental eco-friendly
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