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Produktbild: Selection Bias and Covariate Imbalances

Selection Bias and Covariate Imbalances

Aus der Reihe Statistics in Practice

108,99 €

inkl. gesetzl. MwSt., Versandkostenfrei

Beschreibung

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

01.06.2005

Verlag

John Wiley & Sons

Seitenzahl

224

Maße (L/B/H)

23,5/15,7/1,7 cm

Gewicht

478 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-0-470-86362-6

Beschreibung

Rezension

"...recommended to all practitioners and researchers in thefield of clinical trials..." ( Biometrics , December 2005)
" ... informative and interesting to read" (Phamaceutical Statistics Volume 5:2)

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

01.06.2005

Verlag

John Wiley & Sons

Seitenzahl

224

Maße (L/B/H)

23,5/15,7/1,7 cm

Gewicht

478 g

Auflage

1. Auflage

Sprache

Englisch

ISBN

978-0-470-86362-6

Herstelleradresse

Libri GmbH
Europaallee 1
36244 Bad Hersfeld
DE

Email: gpsr@libri.de

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  • Produktbild: Selection Bias and Covariate Imbalances
  • Preface.
     
    Part I: Is There a Problem with Reliability in Medical Studies?
     
    1 An Evolution of Comparative Methodology.
     
    1.1 Single-subject studies.
     
    1.2 Case series and cohort studies.
     
    1.3 Historical controls.
     
    1.4 Parallel control groups.
     
    1.5 Matched studies.
     
    1.6 Randomization.
     
    1.7 Advance randomization.
     
    1.8 Allocation concealment.
     
    1.9 Residual selection bias.
     
    2 Susceptibility of Randomized Trials to Subversion and Selection Bias.
     
    2.1 Can randomized trials be subverted?
     
    2.2 If randomized trials are subverted, do they cease to be randomized trials?
     
    2.3 What is masking?
     
    2.4 What is allocation concealment?
     
    2.5 A double standard.
     
    2.6 What if allocation concealment could be ensured?
     
    3 Evidence of Selection Bias in Randomized Trials.
     
    3.1 The burden of proof regarding the existence of selection bias in randomized trials.
     
    3.2 Indirect population-level evidence that selection bias exists in randomized trials.
     
    3.3 Direct trial-level evidence that selection bias exists in randomized trials.
     
    3.4 In search of better evidence.
     
    4 Impact of Selection Bias in Randomized Trials.
     
    4.1 Quantifying the prediction of future allocations: balanced blocks.
     
    4.2 Quantifying prediction of future allocations: unbalanced blocks.
     
    4.3 Quantifying covariate imbalance resulting from selection bias.
     
    4.4 Quantifying the bias resulting from covariate imbalance.
     
    Part II: Actions to be Taken to Improve the Reliability of Medical Studies.
     
    5 Preventing Selection Bias in Randomized Trials.
     
    5.1 Minimizing the Impact of Selection Bias.
     
    5.2 Biased Selection of Investigators.
     
    5.3 Minimizing the prediction of future allocations.
     
    6 Detecting Selection Bias in Randomized Trials.
     
    6.1 Baseline Imbalances in Observed Covariates.
     
    6.2 Testing for selection bias without baseline analyses.
     
    6.3 The selection covariate.
     
    6.4 The role of the reverse propensity score in third-order residual selection bias.
     
    6.5 Using the reverse propensity score To Test for selection bias: the Berger-Exner test and graph.
     
    6.6 Using the screening log to test for selection bias.
     
    6.7 The Ivanova-Barrier-Berger (IBB) Detection Method.
     
    6.8 Interpreting negative tests of selection bias.
     
    6.9 When should one test for selection bias?
     
    6.10 Who should test for selection bias?
     
    7 Adjusting for Selection Bias in Randomized Trials.
     
    7.1 Methods proposed for addressing non-random baseline imbalances.
     
    7.2 Selection bias arising from a complete lack of allocation concealment.
     
    7.3 Selection bias arising from imperfect allocation concealment.
     
    8 Managing Selection Bias in Randomized Trials.
     
    8.1 Action points during the design phase of the trial.
     
    8.2 Action points during the conduct of the trial.
     
    8.3 Action points during the analysis of trial data.
     
    8.4 Action points by party.
     
    References.
     
    Author Index.
     
    Subject Index.