Fazwi Yahya, Falih H. Musa, Huda A.F. AL-Bayti

Synthesis and identification of new derivatives of L-ascorbic acid

derivatives of L-ascorbic acid

• Broschiertes Buch

Produktbeschreibung

In this work, three new derivatives (ligands) of L-ascorbic acid (vitamin C) and their metal complexes have been synthesized and characterized. The first ligand is Bis[O,O-2,3;O,O-5,6-(N,N-dicarboxylicmethylidene)-N-2-methylene pyridyl]-L-ascorbic acid (LP), was synthesized by the reaction of Bis[O,O-2,3;O,O-5,6-(chloro(carboxylic)methylidene)]-L-ascorbicacid (starting material) with one mmole 2-Picolylamine. The second ligand is Bis[O,O-2,3;O,O-5,6-(thiol(carboxylic)methylidene)]-L-ascorbic acid (LS), was synthesized by the reaction of Bis[O,O-2,3;O,O-5,6-(chloro (carboxylic)methylidene)]-L-ascorbic with excess of sodium sulfide. The third ligand is Bis[O,O-2,3;O,O-5,6-(acetate(carboxylic) methylidene)]-L-ascorbic acid (LA), was performed by the reaction of Bis[O,O-2,3;O,O-5,6-(chloro (carboxylic)methylidene)]-L-ascorbic acid with two mmoles sodium acetate and The biological activities of these ligands LP, LS, LA and some of their complexes which are (Co2+, Cu2+, Cd2+) performedagainst two types of pathogenic bacteria are Staphylococcus aureus (Gram Positive) and Escherichia coli (Gram Negative) in a nutrient agar medium.

Produktdetails

• Verlag: Scholar's Press
• Seitenzahl: 184
• Erscheinungstermin: 2. November 2016
• Englisch
• Abmessung: 220mm x 150mm x 12mm
• Gewicht: 292g
• ISBN-13: 9783659844416
• ISBN-10: 3659844411
• Artikelnr.: 47109670

Autorenporträt

Dr.Fazwi Yaha Faculty of Science, University of Kufa