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The book contains a review of literature and our own experimental data on the effect of flavonoids on cell functions, mainly mitochondria. The modern concepts of flavonoids on human and animal organisms in norm and pathology are reviewed. The biological role of mitochondria and the involvement of mitochondria in the formation of hydrogen peroxide are then outlined. The influence of flavonoids on cell energy metabolism and lipid peroxidation processes. The role of lipids in the structure and function of mitochondrial membranes is discussed. The data on the effects of flavones on respiration, oxidative phosphorylation, and the activity of oxidase systems of the mitochondrial respiratory chain are then outlined. The effects of flavones on lipid peroxidation, phospholipid metabolism, and the activity of lipolytic enzymes of mitochondrial membranes are discussed. Finally, the last chapter summarizes the results of the study of the effects of flavones on energy and lipid metabolism in the mitochondrial membrane.