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Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect…mehr
Since the very beginning of critical care medicine, much attention has been paid to the risk of bleeding, but only recently the risk of thrombosis has been recognized in critical patients; in fact, current laboratory investigations aimed to monitor blood coagulation are more focused on the assessment of the hemorrhagic than of the thrombotic risk. Since mid-90s, many studies have detected powerful pro-thrombotic actions of endogenous mediators in sepsis and other inflammatory conditions, including trauma and postoperative status. Unfortunately, the related complication are both hard to detect and extremely harmful. The volume provides a full coverage of the hemocoagulative problems in anesthesia and intensive care, taking into consideration the physiology and monitoring of hemostasis, its relation with sepsis, and the specific aspects of the various critical conditions - from trauma to burns, to heart and transplant surgery or acute renal failure.
Physiology of Hemostasis.- Monitoring of Hemostasis.- Anticoagulation therapy in ICU patients.- Inborn Pro-Thrombotic States.- Inborn Defects of the Coagulative System.- Inflammation and Coagulation.- Disseminated Intravascular Coagulation.- Coagulative Disturbancies in Trauma.- Hypothermia and coagulative disorders.- Hemostasis in Pregnancy and in Obstetric Surgery.- Hemostasis During Heart Surgery.- Hemostasis During Transplant Surgery.- Antiphospholipid Antibody Syndrome.- Pulmonary-Renal Syndrome.- Coagulative Disorders after Central Nervous System injury.
1. Physiology of Hemostasis 2. Basic Monitoring of Hemostasis (Giansante) 3. Advanced Monitoring of Hemostasis the Thromboelastogram (Vincenti) 4. Drugs and Hemostasis (Berlot et al) 5. Inborn Prothrombotic States (Giansante) 6. Inborn Defects of the Coagulation System 7. Fluid Resuscitation and Hemostasis (Berlot et al) 8. Hemostasis and Sepsis 9. Disseminated Intravascular Coagulation (Gullo et al) 10. Hemostasis in Trauma and Emergency (Berlot et al) 11. Hemostasis in Burns (to be assigned) 12. Hemostasis in Massively Transfused Patients (Nardi) 13. Hemostasis during Hypothermia (Campanile) 14. Hemostasis in Pregnancy and Obstetric Surgery (Astuto) 15. Hemostasis during Heart Surgery (Tritapepe) 16. Hemostasis during Transplant Surgery (Degasperis) 17. Hemostasis in Acute Renal Failure and Renal Replacement Therapies (Ronco) 18. Hemostasis in Rare Critical Conditions (Berlot et al ) 19. Prophylaxis of Deep Venous Thrombosis (Berlot et al)
Physiology of Hemostasis.- Monitoring of Hemostasis.- Anticoagulation therapy in ICU patients.- Inborn Pro-Thrombotic States.- Inborn Defects of the Coagulative System.- Inflammation and Coagulation.- Disseminated Intravascular Coagulation.- Coagulative Disturbancies in Trauma.- Hypothermia and coagulative disorders.- Hemostasis in Pregnancy and in Obstetric Surgery.- Hemostasis During Heart Surgery.- Hemostasis During Transplant Surgery.- Antiphospholipid Antibody Syndrome.- Pulmonary-Renal Syndrome.- Coagulative Disorders after Central Nervous System injury.
1. Physiology of Hemostasis 2. Basic Monitoring of Hemostasis (Giansante) 3. Advanced Monitoring of Hemostasis the Thromboelastogram (Vincenti) 4. Drugs and Hemostasis (Berlot et al) 5. Inborn Prothrombotic States (Giansante) 6. Inborn Defects of the Coagulation System 7. Fluid Resuscitation and Hemostasis (Berlot et al) 8. Hemostasis and Sepsis 9. Disseminated Intravascular Coagulation (Gullo et al) 10. Hemostasis in Trauma and Emergency (Berlot et al) 11. Hemostasis in Burns (to be assigned) 12. Hemostasis in Massively Transfused Patients (Nardi) 13. Hemostasis during Hypothermia (Campanile) 14. Hemostasis in Pregnancy and Obstetric Surgery (Astuto) 15. Hemostasis during Heart Surgery (Tritapepe) 16. Hemostasis during Transplant Surgery (Degasperis) 17. Hemostasis in Acute Renal Failure and Renal Replacement Therapies (Ronco) 18. Hemostasis in Rare Critical Conditions (Berlot et al ) 19. Prophylaxis of Deep Venous Thrombosis (Berlot et al)
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