This chapter describes the use of advanced econometrics methods such as panel data, adaptive models of time series and models of binary and of multinomial unordered choices for the same purpose.The control requirements for the normalized indicators of water quality in water bodies is carried out periodic sampling and analysis of water from surface water bodies.The research on modelling of time series of indicators of natural environments use various methods, including factorial and regression analysis, methods of self-organization of predictive models, machine time series, panel data. Also, to determine the class of pollution, where the qualitative variables, it is advisable to use models of binary choice and multinomial unordered choices.