Evaluation of the Curative Probability of Bioactive Metabolites - M. Abdel-Azeem, Ahmed;Omran, Mohamed A.;Abdel-Zaher Mohamed, Randa
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Medicinal plants had been used to isolate and characterize directly the bioactive metabolites. However, the discovery of fungal endophytes inside these plants with capacity to produce the same compounds shifted the focus of new drug sources from plants to fungi. Bioactive natural products from endophytic fungi, isolated from different plant species, are attracting considerable attention from natural product chemists and biologists alike which is clearly depicted by the steady increase of publications devoted to this topic during the recent years. This study highlighted the biochemical…mehr

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Produktbeschreibung
Medicinal plants had been used to isolate and characterize directly the bioactive metabolites. However, the discovery of fungal endophytes inside these plants with capacity to produce the same compounds shifted the focus of new drug sources from plants to fungi. Bioactive natural products from endophytic fungi, isolated from different plant species, are attracting considerable attention from natural product chemists and biologists alike which is clearly depicted by the steady increase of publications devoted to this topic during the recent years. This study highlighted the biochemical potential of endophytic fungi with focus on detection of the curative probability of their bioactive metabolites against paracetamol-induced liver injury in mice.
Autorenporträt
Ahmed M. Abdel-Azeem é um micólogo da Universidade do Canal de Suez. A sua investigação inclui o isolamento, identificação e avaliação taxonómica destes fungos, com particular ênfase nos taxa produzem materiais bioactivos de diferentes habitats ecológicos, tais como endófitos como uma casa do tesouro de compostos bioactivos de importância medicinal.