Handbook of Statistical Genetics - Balding, David J. / Cannings, Chris / Bishop, Martin (eds.)
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The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide…mehr

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Produktbeschreibung
The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance.
As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research.

Table of contents:
List of contributors
Editor's Preface to the Third Edition
Glossary of Terms
Abbreviations and Acronyms
Chromosome Maps
Statistical Significance in Biological Sequence
Bayesian Methods in Biological Sequence Analysis
Statistical Approaches in Eukaryotic Gene Prediction
Comparative Genomics
Analysis of Microarray Gene Expression Data
Inferences from microarray data
Bayesian methods for microarray data
eQTL analyses
Protein Structure
Metabonomics
Adaptive Molecular Evolution
Genome Evolution
Probabilistic Models for the Study of Protein Evolution
Application of the Likelihood Function in Phylogenetic
Phylogenetics: Parsimony, Networks and Distances
Evolutionary Quantitative Genetics
Quantitative Trait Loci in Inbred Lines
Mapping Quantitative Trait Loci Outbred Pedigrees
Inferences from Mixed Models in Quantitative Genetics
Marker-Assisted Selection and Introgression
Mathematical Models in Population Genetics
Inference, simulation and enumeration of pedigrees and genealogies
Graphical modelling in genetics
Coalescent Theory
Inference Under the Coalescent
Linkage Disequilibrium, recombination and selection
Inferences from Spatial Population Genetics
Analysis of Population Subdivision
Conservation Genetics
Human population genetics/history
Epidemiology and Genetic Epidemiology
Linkage Analysis
Nonparametric Linkage
Admixture mapping and population structure in association studies
Population Association
Genome-wide association studies
Family-based association studies
Cancer genetics
Epigenetics
Ethics
Insurance
Forensics
Reference Author Index
Subject Index.